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by giftsplash
Tue Feb 04, 2020 11:07 am
Forum: Science and Research
Topic: Does having APOE4 protect you from getting the Coronavirus? .... Maybe
Replies: 27
Views: 3890

Does having APOE4 protect you from getting the Coronavirus? .... Maybe

Concept I want to share with the group. It seems that there is a genetic component to the CoronaVirus. Although it is too early to tell but people who catch the virus outside of China seem to be able to survive at a much higher rate. Better medical care might be one reason, but genetics might be ano...
by giftsplash
Wed Oct 30, 2019 11:59 pm
Forum: Science and Research
Topic: Higher phosphatidylcholine protects against dementia
Replies: 55
Views: 8014

Re: Higher phosphatidylcholine protects against dementia

dentification of dietary phosphatidylcholine metabolites as markers for increased CVD risk
'

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086762/
by giftsplash
Sat Oct 26, 2019 10:49 am
Forum: Prevention and Treatment
Topic: APOE and the Association of Fatty Acids With the Risk of Stroke, Coronary Heart Disease, and Mortality
Replies: 1
Views: 718

APOE and the Association of Fatty Acids With the Risk of Stroke, Coronary Heart Disease, and Mortality

What is everyone's take on this study? Conclusions— These exploratory results suggest that APOE-ε4 carriers may be more susceptible to the beneficial or adverse impact of fatty acids on cardiovascular disease and mortality. In this subgroup, higher linoleic acid was protective for stroke and mortali...
by giftsplash
Fri Dec 07, 2018 12:51 pm
Forum: Science and Research
Topic: Dr. Rhonda: Get some DHA in phospholipid form
Replies: 76
Views: 16117

Re: Dr. Rhonda: Get some DHA in phospholipid form

Does this mean it is now safe to take Nordic Naturals - Omega-3 Phospholipids due to them stripping out the Neu5Gc?
by giftsplash
Thu Apr 05, 2018 11:42 pm
Forum: Prevention and Treatment
Topic: Found out I carry the PSEN1 gene is this a death sentence?
Replies: 27
Views: 5455

Re: Found out I carry the PSEN1 gene is this a death sentence?

I think if we can live another 10 years, CRISPR technology should be far along to do successful gene editing (including APOE4).
And with RNA-targeting enzyme the BBB should not be a problem, which could not be said for Cas9 just a year or so ago.
by giftsplash
Mon Apr 02, 2018 7:26 pm
Forum: Prevention and Treatment
Topic: Found out I carry the PSEN1 gene is this a death sentence?
Replies: 27
Views: 5455

Re: Found out I carry the PSEN1 gene is this a death sentence?

Wanted to give everyone an update on my status. I found out through Prometheus that I carry the PSEN-1 mutation. After speaking to a genome counselor I found out that this guarantees that I will have early onset of dementia. My first glimmer of hope came when I ran my girlfriends DNA through Prometh...
by giftsplash
Sun Dec 17, 2017 9:02 pm
Forum: Prevention and Treatment
Topic: Found out I carry the PSEN1 gene is this a death sentence?
Replies: 27
Views: 5455

Re: Found out I carry the PSEN1 gene is this a death sentence?

It's been a tough week. I am still waiting for a genome counselor to do full analytics. I did verify that neither of my parents carry the PSEN1 mutation. However I am not sure if that offers any solace. Maybe someone can shine some light on this http://journals.plos.org/plosmedicine/article?id=10.13...
by giftsplash
Fri Dec 08, 2017 4:15 pm
Forum: Prevention and Treatment
Topic: Found out I carry the PSEN1 gene is this a death sentence?
Replies: 27
Views: 5455

Re: Found out I carry the PSEN1 gene is this a death sentence?

Thank you very much for the information, this is why I love these boards. I will need to take a few days to absorb everything. If anyone else has any info it would be apreciated.
by giftsplash
Thu Dec 07, 2017 6:43 pm
Forum: Prevention and Treatment
Topic: Found out I carry the PSEN1 gene is this a death sentence?
Replies: 27
Views: 5455

Re: Found out I carry the PSAN1 gene is this a death sentence?

Nobody in my family ever had Alzheimer's my dad is apoe4/4 and is 72 and still very sharp. But he does not have PSEN1 gene we just checked this evening.
Not sure if this information helps you.
by giftsplash
Thu Dec 07, 2017 5:39 pm
Forum: Prevention and Treatment
Topic: Found out I carry the PSEN1 gene is this a death sentence?
Replies: 27
Views: 5455

Found out I carry the PSEN1 gene is this a death sentence?

Found out today that I carry the rs63750590(A;G) gene, I am 48 and have always been a little forgetful of names but nothing that I would consider a problem.
Is there any recommendations you can suggest. I am also APOE 3/4

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