Search found 42 matches

by grommet
Tue Jan 30, 2024 2:03 pm
Forum: Science and Research
Topic: elevated LDL from fasting versus exogenous fat consumption
Replies: 10
Views: 1481

Re: elevated LDL from fasting versus exogenous fat consumption

The only study I’m aware of is from the so-called “Lean Mass Hyperesponder” crowd: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048595/ This is a very controversial area of study, with one crowd claiming that ultra-high cholesterol in otherwise metabolically healthy people following a ketogentic di...
by grommet
Tue Jan 30, 2024 1:58 pm
Forum: Science and Research
Topic: Our first guest: Dr. Thomas Dayspring...
Replies: 181
Views: 83730

Re: Our first guest: Dr. Thomas Dayspring...

Does the hypothesis that LDL/ApoB causes dementia rely upon the hypothesis that LDL/ApoB causes arteriosclerosis? Essentially, if LDL harms blood vessels, poor circulation will impair the brain? I wonder if anyone is aware of a compelling study that demonstrates dementia causation directly. Dayspri...
by grommet
Wed Jul 19, 2023 12:44 pm
Forum: Science and Research
Topic: BMJ: Menopausal hormone therapy and dementia: nationwide, nested case-control study
Replies: 3
Views: 928

BMJ: Menopausal hormone therapy and dementia: nationwide, nested case-control study

Hi y’all, the attached study indicates that there’s a positive correlation b/w women taking HRT and all-cause dementia, including Alzheimers. https://www.bmj.com/content/381/bmj-2022-072770 Conclusions Menopausal hormone therapy was positively associated with development of all cause dementia and Al...
by grommet
Sun Mar 26, 2023 7:57 am
Forum: Prevention and Treatment
Topic: Is anyone on an Ezetimibe (Zetia) mono therapy?
Replies: 6
Views: 943

Re: Is anyone on an Ezetimibe (Zetia) mono therapy?

I am on the same journey, doing my cholesterol balance test next week. I am either a hyper absorber or responder or both. Through low saturated fat diet I was able to bring my numbers into a better place but still LDL is 140 and Apoeb is 100, lp(a) and others are great. Once I get the test back I w...
by grommet
Mon Mar 06, 2023 8:40 am
Forum: Prevention and Treatment
Topic: Is anyone on an Ezetimibe (Zetia) mono therapy?
Replies: 6
Views: 943

Re: Is anyone on an Ezetimibe (Zetia) mono therapy?

I'm a hyperabsorber as well as many of our E4 members, but don't feel the need to do anything about it as my lipids always look really good, i.e. ratios, LDL-P, etc. Would you mind sharing more of your results with us? I notice your overall cholesterol is quite low. Perhaps your overall risk is low...
by grommet
Tue Feb 28, 2023 12:30 pm
Forum: Prevention and Treatment
Topic: Is anyone on an Ezetimibe (Zetia) mono therapy?
Replies: 6
Views: 943

Re: Is anyone on an Ezetimibe (Zetia) mono therapy?

Dr. Thomas Dayspring (who y'all know) recommended in the Attia podcast that he wants to see Desmosterol > 1 for his ApoE4 patients, hence my question.
by grommet
Tue Feb 28, 2023 12:25 pm
Forum: Prevention and Treatment
Topic: Is anyone on an Ezetimibe (Zetia) mono therapy?
Replies: 6
Views: 943

Is anyone on an Ezetimibe (Zetia) mono therapy?

I just got my heart balance test results back and unsurprisingly I'm showing as a slight hyperabsorber (screenshot attached). Would it make sense to get a Zetia Rx for this use case? I'm currently on a super low dose Crestor (5 mg, 3x week) because I don't want to impact Desmosterol production due t...
by grommet
Sun Jan 22, 2023 8:10 am
Forum: Science and Research
Topic: Study: Hormone replacement therapy is associated with improved cognition and larger brain volumes in at-risk APOE4 women
Replies: 3
Views: 658

Re: Study: Hormone replacement therapy is associated with improved cognition and larger brain volumes in at-risk APOE4 w

“ Have you seen the Natalie Rasgon Stanford Study that showed Apoe 4 menopausal women benefited from using BHRT?”

I have now! :-) Thanks for your response. There’s lots to catch up on the subject.
by grommet
Wed Jan 18, 2023 5:34 am
Forum: Science and Research
Topic: Study: Hormone replacement therapy is associated with improved cognition and larger brain volumes in at-risk APOE4 women
Replies: 3
Views: 658

Re: Study: Hormone replacement therapy is associated with improved cognition and larger brain volumes in at-risk APOE4 w

My wife is also a double ε4 carrier but is apprehensive about undergoing HRT because of a perceived increased risk in getting breast cancer (her mother had cancer but was also a lifelong smoker). I’m curious what y’all think of this study and if the results are compelling enough to take this serious...