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by MarcR
Tue Oct 31, 2017 2:32 pm
Forum: Science and Research
Topic: Perpetual ketosis considered harmful?
Replies: 6
Views: 312

Perpetual ketosis considered harmful?

A preponderance of native Arctic populations have a genetic polymorphism that prevents them from entering ketosis. As a result, they are awful at fasting - in one study, metabolically healthy children with the SNP in question became clinically hypoglycemic in only 18 hours without food. Chris Master...
by MarcR
Mon Oct 23, 2017 7:29 pm
Forum: Science and Research
Topic: Aces NR3C1methylation.
Replies: 6
Views: 291

Re: Aces NR3C1methylation.

The relationship described in the article among ketamine, BDNF, and hippocampal neuroplasticity causes me to wonder if ketamine could help people suffering from hippocampal atrophy and associated difficulty forming new memories.
by MarcR
Fri Oct 20, 2017 9:06 am
Forum: ApoE4.Info, Inc.
Topic: Site hosting service upgrade this morning
Replies: 0
Views: 130

Site hosting service upgrade this morning

In mid-August traffic to the forums doubled and has maintained the new higher level since. We have noticed occasional periods of sluggish performance, and this week we decided to upgrade the hosting service that supports the site. The upgrade completed about 20 minutes ago. If you notice anything am...
by MarcR
Wed Oct 18, 2017 11:24 am
Forum: Our Stories
Topic: How to gain weight with APOE4
Replies: 28
Views: 880

Re: How to gain weight with APOE4

Thanks, ru442 - I just placed an order. Can't wait!
by MarcR
Wed Oct 18, 2017 10:51 am
Forum: Our Stories
Topic: How to gain weight with APOE4
Replies: 28
Views: 880

Re: How to gain weight with APOE4

He won't eat nuts Nuts vary greatly in flavor and texture, and they are often served mixed. I wonder if you could persuade him to reconsider this exceptionally valuable food category by serving him hyperpalatable Mauna Loa macadamias . (In my experience, macadamias vary widely in quality, much like...
by MarcR
Wed Oct 18, 2017 10:06 am
Forum: Prevention and Treatment
Topic: Forrests, Trees, and Saturated Fat
Replies: 14
Views: 593

Re: Forrests, Trees, and Saturated Fat

You won't find consensus on this topic. While I perceive that most of us believe that saturated fat is harmful, I am not the only member who disagrees. In fact, some of us place saturated fat from pastured animals at the bases of our food pyramids. Have you come across these threads yet? Chris Maste...
by MarcR
Tue Oct 17, 2017 3:26 pm
Forum: Announcements and Events
Topic: Julie - and Dr Bredesen - on Dr Oz show tomorrow
Replies: 35
Views: 1621

Re: Julie - and Dr Bredesen - on Dr Oz show tomorrow

Kudos to Julie and Deborah for eloquence and poise - I'm sure being on the show is much more difficult than you made it look.
by MarcR
Sun Oct 08, 2017 2:32 pm
Forum: Science and Research
Topic: Sleep duration and mortality
Replies: 6
Views: 273

Sleep duration and mortality

Mortality Related to Actigraphic Long and Short Sleep The paper is worth reading in full. Here are two surprising findings: ⋅ Mortality rates were much higher among subjects who slept less than 5 hours or more than 6.5 hours. (Actigraphic sleep measurements average 52 minutes less than se...
by MarcR
Sat Oct 07, 2017 1:51 pm
Forum: Science and Research
Topic: Stavia's High Saturated Fat experiment
Replies: 61
Views: 2995

Re: RE: Re: Stavia's High Saturated Fat experiment

Stavia wrote:Breakfast: 2 ounces macadamia nuts and 4 ounces bone marrow....eggs on the boil....dogs waiting for the whites ...
Yum!
by MarcR
Mon Sep 25, 2017 5:22 pm
Forum: Science and Research
Topic: Minding our Mitochondria
Replies: 17
Views: 1016

Re: Minding our Mitochondria

Many thanks to Julie and Russ for the two excellent Bressan/Kramer papers.

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