When I ask him about factors mentioned by Bredesen in Type 3 diabetes Joe, I want to be sure that I communicated this point about Type 3 Alzheimer's effectively. Bredesen's schema includes four types of Alzheimer's: ⋅  Type 1 : Inflammatory. Chronic inflammation, often abetted by an overa...

Joe, I agree with Tincup that you don't seem insulin resistant. Do you continue to meet the criteria for a positive dementia diagnosis today? If so, I wonder if you have something else going on. Are you familiar with Dale Bredesen's Type 3 Alzheimer's classification?

The problem. If you use a device running an Android version prior to 7.1.1, beginning January 11 your access from that device to this site and many others will be impaired. (7.1.1 was released only four years ago, and a third of all Android devices are running older versions.) When you attempt to v...

I agree that Fiver's summary is excellent and would also like to thank everyone participating in this fantastic topic.

I learned that restless legs can impact deep sleep from my Oura 2 Ring as it measures "restlessness" and that measure has dropped along with improvements in deep sleep. It sounds as though the Oura 2 estimates deep sleep by tracking "restlessness" as a surrogate marker. One of t...

I have been a satisfied monthly subscriber to the Prairie Ground Box since last November. Recommended!

Great handle and first post, apoe4thebetter - welcome. You seem to have a solid strategy and are refining and optimizing rather than fixing big problems - congratulations on being so well-positioned for an extended health span. I imagine that you are familiar with Dave Feldman's work, but just in ca...

There is no data showing that MMST facilitates elimination of aluminum from the body. This 2018 paper addressed that question: Anti-Aging Effects of Monomethylsilanetriol and Maltodextrin-Stabilized Orthosilicic Acid on Nails, Skin and Hair Because it was cosmetics research, it analyzed aluminum co...

Laurie, what does Dennis think of monomethylsilanetriol as a silica source? It's expensive relative to the home chemistry recipe, but it's way more convenient. Here's a source for the Orgono product, and here are some relevant references: The silicon supplement ‘Monomethylsilanetriol’ is safe and in...

Dave Feldman has documented large day-by-day lipid differences related to dietary changes via extensive self-testing. He has developed a theory - the lipid energy model - to explain that variability along with other important discrepancies between the conventional wisdom and what the world's collect...