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by MarcR
Fri Dec 06, 2019 8:40 am
Forum: Our Stories
Topic: I'm a newbie!! My intro.
Replies: 2
Views: 116

Re: I'm a newbie!! My intro.

Welcome, Paige! Are you familiar with Dave Feldman's work? His site is Cholesterol Code , and a vibrant affiliated community of people striving to understand the implications of higher lipid levels in conjunction with overall strength and well being has formed on Facebook at Lean Mass Hyper-responde...
by MarcR
Wed Nov 27, 2019 3:17 pm
Forum: Science and Research
Topic: Attia email: LDL-C, blood pressure, and CVD risk
Replies: 18
Views: 380

Re: Attia email: LDL-C, blood pressure, and CVD risk

Parsing your words ... leaves out Statin users(which makes the study flawed) Exclude statin users = "study flawed" if you leave the statin users in you are again confounding Include statin users = "confounding" By this logic, all lipid studies conducted since the inception of sta...
by MarcR
Wed Nov 27, 2019 2:09 pm
Forum: Science and Research
Topic: Attia email: LDL-C, blood pressure, and CVD risk
Replies: 18
Views: 380

Re: Attia email: LDL-C, blood pressure, and CVD risk

Great point, NewRon. I split the topic at the point that the link to Attia's email, which was about CVD risk, not Alzheimer's, was introduced.
by MarcR
Wed Nov 20, 2019 11:10 am
Forum: Science and Research
Topic: Attia email: LDL-C, blood pressure, and CVD risk
Replies: 18
Views: 380

Re: Blood Pressure Treatment Drastically Reduces Alzheimer’s Incidence

They left out Statin users thereby confounding the population pool they sampled from. This results in a sampling bias as the high cholesterol portion that has high cardiovascular risk would be left out. The entire study screened out people with existing diabetes and heart disease, so the statin use...
by MarcR
Fri Nov 15, 2019 12:02 pm
Forum: Getting Started
Topic: Saying hi and needing help
Replies: 8
Views: 328

Re: Saying hi and needing help

if saturated fats are bad for those with the APO4 gene Just a quick note to let you know that consensus on this point does not exist. Here's a topic linking and discussing a noted nutrition scientist's views: Chris Masterjohn on saturated fat Because some members notice that their LDL-C levels rise...
by MarcR
Fri Nov 15, 2019 11:44 am
Forum: Science and Research
Topic: Attia email: LDL-C, blood pressure, and CVD risk
Replies: 18
Views: 380

Re: Blood Pressure Treatment Drastically Reduces Alzheimer’s Incidence

That looks like a terrific new paper, Susan - great find! I didn't have any luck acquiring the full paper as it does not yet seem to be on Sci-Hub . Fortunately the abstract does a great job of hitting the high points. So there might be a corollary that you don't want high LDL with the presence of i...
by MarcR
Thu Nov 14, 2019 6:26 pm
Forum: Science and Research
Topic: Attia email: LDL-C, blood pressure, and CVD risk
Replies: 18
Views: 380

Re: Blood Pressure Treatment Drastically Reduces Alzheimer’s Incidence

all things equal a lower LDL equates to a lower CHD-CVD risk. The evidence suggests otherwise. This 8-year study of 100,000+ people aged 50+ without preexisting diabetes or heart disease is the only high-powered study I have seen that focuses on the lipids of healthy older people. I am skeptical of...
by MarcR
Tue Nov 12, 2019 4:16 pm
Forum: Science and Research
Topic: Attia email: LDL-C, blood pressure, and CVD risk
Replies: 18
Views: 380

Re: Blood Pressure Treatment Drastically Reduces Alzheimer’s Incidence

Attia emphasizes the "mental gymnastics" required to understand Mendelian randomization (MR) and suggests that those of us who are intimidated by the work required ... I had to print it out, put a spreadsheet together, and build my own model to fully digest it. It took a lot longer than I ...
by MarcR
Mon Nov 04, 2019 8:56 am
Forum: ApoE4.Info, Inc.
Topic: Alzheimer's and "Death with Dignity"
Replies: 28
Views: 5815

Re: Alzheimer's and "Death with Dignity"

Washington Post article about a 94-year-old who fasted to hasten death. Her daughter made a short film of the experience: https://wapo.st/2PJl2nW
by MarcR
Wed Sep 18, 2019 10:36 am
Forum: Prevention and Treatment
Topic: Xcode Life vs Promethease and other raw data analyzers
Replies: 32
Views: 1798

Re: Xcode Life vs Promethease and other raw data analyzers

This topic attracted a couple of new members seeking to advertise the Xcode Life raw dna data analysis service. (The moderation team thwarted their efforts.) I believe Xcode Life is a scam site. It pains me to see it listed first in this topic name as it is not in the same league as the services off...

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