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by marty
Fri Jan 20, 2017 1:20 pm
Forum: Science and Research
Topic: CSF Ferritin predicts cognitive decline in E4s
Replies: 115
Views: 28398

Re: CSF Ferritin predicts cognitive decline in E4s

It's hard to know where to begin. But this is an important study. First, I don't see the value of checking the serum ferritin level. It does not tell you the brain iron status. Period. The only value it may have is if you were not sure it would be safe to decrease your iron intake. If the serum ferr...
by marty
Wed Jan 11, 2017 1:38 pm
Forum: Science and Research
Topic: Scientific American interview with Dr. Fillit
Replies: 3
Views: 1387

Scientific American interview with Dr. Fillit

https://blogs.scientificamerican.com/talking-back/new-alzheimer-rsquo-s-treatments-offer-hope-despite-recent-drug-failures/?utm_source=Newsletter%2C+Donors%2C+Events%2C+General&utm_campaign=f5983f3cce-news17_1.11&utm_medium=email&utm_term=0_cc5f9da121-f5983f3cce-97061357&goal=0_cc5f9...
by marty
Mon Jan 09, 2017 5:17 pm
Forum: Science and Research
Topic: Youthful Brains in Older Adults: Preserved Neuroanatomy in the Default Mode and Salience Networks...
Replies: 10
Views: 2873

Re: Youthful Brains in Older Adults: Preserved Neuroanatomy in the Default Mode and Salience Networks...

I have to agree with all you said, Stavia.

I have a collection of a few dozen courses. There hasn't been a disappointment yet.
by marty
Mon Jan 09, 2017 10:40 am
Forum: Science and Research
Topic: Youthful Brains in Older Adults: Preserved Neuroanatomy in the Default Mode and Salience Networks...
Replies: 10
Views: 2873

Re: Youthful Brains in Older Adults: Preserved Neuroanatomy in the Default Mode and Salience Networks...

So the idea may be to find something challenging and engaging without engendering fear of failure. Learning a musical instrument is a possibility, especially if you don't mind never amounting to much with it. Another approach I enjoy is watching lectures from The Great Courses. http://www.thegreatco...
by marty
Sun Jan 08, 2017 9:35 am
Forum: Prevention and Treatment
Topic: Melatonin
Replies: 45
Views: 10047

Re: Melatonin

Here are a few comments. Cortisol levels should be at their peak in the morning. Sleep apnea, chronic insomnia and a longer fast can elevate them. And the normal for an individual can vary a lot. Lots of possibilities. Controlled studies of melatonin for chronic insomnia show only a small benefit. T...
by marty
Sun Jan 08, 2017 9:13 am
Forum: Prevention and Treatment
Topic: Melatonin
Replies: 45
Views: 10047

Re: Melatonin

I can't comment on Consumer Lab specifically. It may be credible. Beware that some "labs" are non-existent or are paid by the manufacturing or importing company for an endorsement. If there is advertising on the website that says it did the analysis, be very suspicious. Another concern is ...
by marty
Sun Jan 08, 2017 9:03 am
Forum: Our Stories
Topic: Neurologist and a 4/4
Replies: 19
Views: 4512

Re: Neurologist and a 4/4

Pretty much all major studies have confidentiality agreements to limit divulgence of design of the study. There are different reasons for this, but one of them is to prevent competing groups from unfair advantage. There are egos, patents, and money involved, like in most human endeavors. What I can ...
by marty
Fri Jan 06, 2017 3:01 pm
Forum: Science and Research
Topic: Mind your ApoA1 levels!
Replies: 21
Views: 5125

Re: Mind your ApoA1 levels!

[quote="Juliegee"]Marty, many of us are following the cardiovascular angle too. So far, it looks though pharmaceutically induced higher HDL levels are of little to no value. For now, looks like HDL has to be earned the old fashioned way. The relationship between HDL and neurodegeneration i...
by marty
Fri Jan 06, 2017 8:07 am
Forum: Science and Research
Topic: Mind your ApoA1 levels!
Replies: 21
Views: 5125

Re: Mind your ApoA1 levels!

This is another piece in a large puzzle. I wonder what it means. My initial reaction is to think about the association of higher HDL with protection against heart disease. That association begged the question as to whether increasing HDL in patients prevents heart disease. So far, the major studies ...
by marty
Thu Jan 05, 2017 3:54 pm
Forum: Prevention and Treatment
Topic: Melatonin
Replies: 45
Views: 10047

Melatonin

Dr. Bredesen incorporates melatonin into his protocol, which makes good sense. But it's not that simple. Normal melatonin blood levels increase an hour or longer before bedtime and they are sustained throughout the night. So far, so good. Exogenous melatonin often creates unpredictable blood levels....

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