Search found 1336 matches

Go to advanced search

by TheBrain
Thu Apr 23, 2020 5:17 am
Forum: Prevention and Treatment
Topic: Dutch Woman With Dementia Euthanized Against Her Will. The Doctor Was Just Cleared Of Wrongdoing.
Replies: 24
Views: 2267

Re: Dutch Woman With Dementia Euthanized Against Her Will. The Doctor Was Just Cleared Of Wrongdoing.

It seems the case in the original post has been clarified in the courts: Dutch court allows euthanasia in advanced dementia cases Thanks, circular. The original reporting contradicts what’s stated in the latest article (the first page contains the link for this thread): And in the case of this spec...
by TheBrain
Wed Apr 22, 2020 12:57 pm
Forum: Science and Research
Topic: How do specificity and sensitivity work with lab testing?
Replies: 8
Views: 372

Re: How do specificity and sensitivity work with lab testing?

Tincup wrote:One thing to note, with a 1% prevalence, if you test false, the probability that you've not had the bug is very near 100%. In my 1 million case example. There are only 100 false negatives out of nearly 1 million.


Thanks for this and your previous post. My head has finally wrapped this matter.
by TheBrain
Wed Apr 22, 2020 12:56 pm
Forum: Science and Research
Topic: How do specificity and sensitivity work with lab testing?
Replies: 8
Views: 372

Re: How do specificity and sensitivity work with lab testing?

I found Peter Attia's explanation and modifiable spread sheet helpful. The accuracy of lab tests depends on how common the condition is in the community (prevalence). Thanks, Slacker. I didn't see your post until I submitted my response to Tincup. I'll take a look. Great video! Peter Attia explains...
by TheBrain
Wed Apr 22, 2020 8:49 am
Forum: Science and Research
Topic: How do specificity and sensitivity work with lab testing?
Replies: 8
Views: 372

Re: How do specificity and sensitivity work with lab testing?

slacker wrote:I found Peter Attia's explanation and modifiable spread sheet helpful. The accuracy of lab tests depends on how common the condition is in the community (prevalence).


Thanks, Slacker. I didn't see your post until I submitted my response to Tincup. I'll take a look.
by TheBrain
Wed Apr 22, 2020 8:46 am
Forum: Science and Research
Topic: How do specificity and sensitivity work with lab testing?
Replies: 8
Views: 372

Re: How do specificity and sensitivity work with lab testing?

I did the exercise here (see table in link) with this result, and Birx did not misspeak. The issue is the assumption is that 1% are positive AND you are testing everyone. I randomly assumed a grand total of 1,000,000. I used the 99% assumptions. Header Disease_Present Disease_Absent Totals Test_Pos...
by TheBrain
Wed Apr 22, 2020 6:06 am
Forum: Science and Research
Topic: How do specificity and sensitivity work with lab testing?
Replies: 8
Views: 372

How do specificity and sensitivity work with lab testing?

I wasn’t sure where to post this, as it’s related to COVID-19, but I believe my question applies more broadly about lab tests. Below is the article that raises the question for me. I understand that specificity and sensitivity relate to false negatives and false positives. We don’t want either. I’ve...
by TheBrain
Wed Apr 22, 2020 4:38 am
Forum: Science and Research
Topic: KLOTHO: Good news for 20% of us!
Replies: 11
Views: 1247

Re: KLOTHO: Good news for 20% of us!

23andme showed I’m homozygous on the first SNP. It didn’t show the second SNP, but I guess I can assume it’s also homozygous.
by TheBrain
Tue Apr 07, 2020 8:55 am
Forum: Science and Research
Topic: New series of very interesting articles on APOE4
Replies: 2
Views: 1003

Re: New series of very interesting articles on APOE4

Wow, and all 11 articles are downloadable at no charge. Fiver, thanks for posting this!
by TheBrain
Tue Apr 07, 2020 8:44 am
Forum: Prevention and Treatment
Topic: podcast: Gastropod: Can Diet Stop Alzheimer’s?
Replies: 3
Views: 1119

Re: podcast: Gastropod: Can Diet Stop Alzheimer’s?

Thanks, Brian. I look forward to a listen. I was an early fan of Lisa Mosconi; even got to have lunch with her and Stephan Cunane in NY, but have been largely disappointed with her diet recommendations. She has a good handle on the reduction in cerebral glucose utilization issues for our genotype (...
by TheBrain
Sat Mar 28, 2020 7:46 am
Forum: Announcements and Events
Topic: Check out our new podcast
Replies: 40
Views: 3548

Re: Check out our new podcast

Many thanks to Julie, MarcR, Theresa, and Tincup for all their work on this podcast. Great choice having Dr. Wahls as your first guest. I’ll listen during breakfast this morning.

Go to advanced search