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by floramaria
Sun Apr 11, 2021 10:27 am
Forum: Science and Research
Topic: Any updates on rs2075650 with APOE4/4 + family history?
Replies: 3
Views: 130

Re: Any updates on rs2075650 with APOE4/4 + family history?

Thanks, Floramaria, I think that's what the number was back in 2018 too. Maybe that SNP isn't getting the same attention for statistical analysis the way that APOE4 has. Yes, you may be right about that. I did a little poking around the internet and saw a Nov 2020 Meta-Analysis, but not any links t...
by floramaria
Sat Apr 10, 2021 10:06 pm
Forum: Science and Research
Topic: Alzheimer’s risk gene disrupts endocytosis, but another disease-linked gene could help
Replies: 1
Views: 772

Re: Alzheimer’s risk gene disrupts endocytosis, but another disease-linked gene could help

Jmac wrote: And, since I'm now doing ReCode full-blown those pesky nasty genes are going to shut up and watch me thrive!

Hi Jmac, just checking in with you to see how things are going with your full-blown ReCODE. Thriving, I hope!
by floramaria
Sat Apr 10, 2021 9:52 pm
Forum: Prevention and Treatment
Topic: Celebration Thread! Biogen is going to the FDA with Aducan.
Replies: 513
Views: 38351

Re: Celebration Thread! Biogen is going to the FDA with Aducan.

Yes, I think that we now need to be aware that genetic uplift is starting. Life will never be the same. Natural reproduction is no longer plausible. Might not be that long before it is illegal. The idea of simply spinning the genetic roulette wheel is already absurd. Human traits are polygentically...
by floramaria
Sat Apr 10, 2021 9:07 pm
Forum: Our Stories
Topic: Newbie 4/4 trying to stay positive!
Replies: 2
Views: 119

Re: Newbie 4/4 trying to stay positive!

Hello everyone, I am new here having discovered by APOE 4/4 status a couple of days ago. I don’t know much about genetics, but reading through what you found on Promethease, it sounds like you do have some protective genes. I especially like the “longer telemeres, longer life” SNP! That one seems l...
by floramaria
Sat Apr 10, 2021 3:07 pm
Forum: Science and Research
Topic: Any updates on rs2075650 with APOE4/4 + family history?
Replies: 3
Views: 130

Re: Any updates on rs2075650 with APOE4/4 + family history?

I’m curious whether there’s new information on rs2075650 and its correlation with Alzheimer’s. Has anyone seen more recent info on rs2075650 and its impact on Alzheimer’s probabilities? I recently saw a slide in a genetics presentation showing that a Meta-analysis of studies indicate rs2075650 may ...
by floramaria
Thu Apr 08, 2021 2:05 pm
Forum: Prevention and Treatment
Topic: Does Julie Reynolds still take these 4 supps at bedtime??
Replies: 8
Views: 377

Re: Does Julie Reynolds still take these 4 supps at bedtime??

Julie G wrote: FWIW, Dr. Bredesen, Dr. Hathaway and I are doing a FB Live on LDN this Friday at 3PM PT on Dr. Bredesen's page. They'll take live questions if you want to explore this further.
usually I avoid FB but I’ll want to tune in for this! Thanks for mentioning it here.
by floramaria
Thu Apr 08, 2021 2:01 pm
Forum: Science and Research
Topic: Covid vaccine safety for 4/4’s?
Replies: 31
Views: 3309

Re: Covid vaccine safety for 4/4’s?

Does anybody have any information about which vaccine is better for people w/ a 4/4 variant? Would it be better to introduce the mRNA technology than the Johnson and Johnson which contains part of the virus? Or is just being extra cautious and not get the vaccine at all be better? So on the fence!!...
by floramaria
Sun Apr 04, 2021 10:27 pm
Forum: Science and Research
Topic: APOΕ4 Lowers Energy Expenditure and Impairs Glucose Oxidation by Increasing Flux through Aerobic Glycolysis
Replies: 26
Views: 4114

Re: APOΕ4 Lowers Energy Expenditure and Impairs Glucose Oxidation by Increasing Flux through Aerobic Glycolysis

I just got the new iWatch and I’m tracking my oxygen while I sleep. So far so good! I’m hoping to learn more about how HBOT might help get oxygen to the brain...Possibly a useful therapy for Apoe4s. Interesting about the iWatch. I'm an older APOE4/4 and have thought about the new iPhone to track O2...
by floramaria
Sun Apr 04, 2021 10:06 pm
Forum: Science and Research
Topic: Full Genome Sequencing Polygenic Scores Software
Replies: 9
Views: 169

Re: Full Genome Sequencing Polygenic Scores Software

J11 wrote:because I couldn't figure out what I did.

I really have no idea what you did but think this an impressive undertaking!
by floramaria
Tue Mar 30, 2021 9:41 pm
Forum: Our Stories
Topic: New member with some questions...
Replies: 6
Views: 348

Re: New member with some questions...,

I just recently (inadvertently) found out I am APOE3/4 while searching for info about Compound MTHFR , which I also am. In the week since I’ve been researching on this site pretty much non-stop. A little background…I’m female, two weeks from 40. I have no family history of AZ or dementia. I already...

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