Search found 215 matches

by Brian4
Wed Mar 20, 2024 3:05 pm
Forum: Science and Research
Topic: Huge list of therapies / drugs in the pipeline
Replies: 2
Views: 185

Re: Huge list of therapies / drugs in the pipeline

Thanks LondonGirl. I share your short list. (By the way, some 4/4s are making a variation of LX1001 available off-shore.)

Re BCG: Where can one get this?
by Brian4
Mon Mar 11, 2024 6:23 am
Forum: Announcements and Events
Topic: Upcoming Gene Therapy Webinar
Replies: 4
Views: 2441

Re: Upcoming Gene Therapy Webinar

https://ir.lexeotx.com/news-releases/news-release-details/lexeo-therapeutics-reports-fourth-quarter-and-full-year-2023 APOE4-associated Alzheimer’s Disease Programs: Lexeo completed enrollment of all four cohorts in the LEAD Phase 1/2 clinical trial of LX1001 for the treatment of APOE4-associated Al...
by Brian4
Sun Mar 10, 2024 12:25 pm
Forum: Science and Research
Topic: Homotaurine (tramiprosate) appears to be a structure corrector
Replies: 77
Views: 130717

Re: Homotaurine (tramiprosate) appears to be a structure corrector

It's early days with this research, so I'm not sure of anything. But if homotaurine is a structure corrector, I'd want it to correct my apoE4 all the time. ApoE4 might help with brain development, but after childhood, I think its function is likely purely deleterious -- morning, noon, night. But who...
by Brian4
Fri Mar 08, 2024 4:00 am
Forum: Prevention and Treatment
Topic: Methylene Blue AD Cure Celebration Thread!
Replies: 50
Views: 18086

Re: Methylene Blue AD Cure Celebration Thread!

T, thanks. That's what I thought. I confess my kitchen is filled with blue stains, but I think I now know how to put the powder in capsules carefully. It seems like the easiest approach, for me at least. My next question is about getting non-contaminated MB. This was helpful: https://docs.google.com...
by Brian4
Tue Mar 05, 2024 5:36 pm
Forum: Science and Research
Topic: Homotaurine (tramiprosate) appears to be a structure corrector
Replies: 77
Views: 130717

Re: Homotaurine (tramiprosate) appears to be a structure corrector

Aphorist. Good question. The Alzheon studies didn't look at different time of day dosing. I'm not sure it would make a huge difference, but, like you, I haven't yet fully digested the Nemergut paper. I'm aiming for the apoE4 structure corrector function, which makes me want to take homotaurine throu...
by Brian4
Tue Mar 05, 2024 5:33 pm
Forum: Prevention and Treatment
Topic: Methylene Blue AD Cure Celebration Thread!
Replies: 50
Views: 18086

Re: Methylene Blue AD Cure Celebration Thread!

Quick question. Everyone seems to be speaking about taking MB as liquid drops. Is there some reason that is escaping me as to why one couldn't just put the right amount of powder into a capsule and pop the capsule? I have an accurate milligram scale, and lots of capsules.

Thanks,
Brian
by Brian4
Sat Jan 27, 2024 3:04 pm
Forum: Prevention and Treatment
Topic: p tau217
Replies: 5
Views: 735

Re: p tau217

Dr. Bredesen is very excited about this one and is partnering with a company to release a fairly inexpensive version soon.
Great news Julie -- thank you! I look forward to seeing this come to market.
by Brian4
Tue Jan 23, 2024 12:01 pm
Forum: Prevention and Treatment
Topic: p tau217
Replies: 5
Views: 735

p tau217

Has anyone found a way to get a p-tau217 test?

Getting a doctor to sign up here --
https://alzpath.bio/
-- might work, but it's not clear that AlzPath has made the test available yet.

https://jamanetwork.com/journals/jamane ... le/2813751
by Brian4
Wed Dec 27, 2023 3:33 pm
Forum: Prevention and Treatment
Topic: Has anyone else gotten the new Abeta 42/40 test?
Replies: 16
Views: 8492

Re: Has anyone else gotten the new Abeta 42/40 test?

N, thanks. Very helpful background info! I think I'll ignore my (slightly) suboptimal result.
by Brian4
Wed Dec 27, 2023 7:03 am
Forum: Prevention and Treatment
Topic: Has anyone else gotten the new Abeta 42/40 test?
Replies: 16
Views: 8492

Re: Has anyone else gotten the new Abeta 42/40 test?

Thanks everyone, for the helpful thoughts about Quest's 42:40 ratio test. I'm puzzled by their reference range. Here's what their report says about interpreting results: ------------ Plasma beta-amyloid 42/40 ratio Risk Table: Risk of Alzheimer's Disease: Lower Risk: > or = 0.170 Intermediate Risk: ...