Search found 149 matches

by Fc1345linville
Sat Mar 16, 2024 2:08 pm
Forum: Prevention and Treatment
Topic: APOE 4/4 - Wisdom on telling siblings/children
Replies: 7
Views: 1066

Re: APOE 4/4 - Wisdom on telling siblings/children

I have not been active on the Forum in several years, but that is not because of any bad news. In fact, I am in relatively good health. Quick background, I found out I was 4/4 in a surprise 23andMe report in 2013 when I was 71. The good news was that I had chosen a healthy life style in my late 20&q...
by Fc1345linville
Wed Oct 04, 2023 11:34 am
Forum: Science and Research
Topic: Sitting all day increases dementia risk — even if you exercise
Replies: 3
Views: 2619

Re: Sitting all day increases dementia risk — even if you exercise

Thanks Tincup, I will definitely give this a try!

Fc
by Fc1345linville
Tue Oct 03, 2023 10:18 am
Forum: Science and Research
Topic: Sitting all day increases dementia risk — even if you exercise
Replies: 3
Views: 2619

Sitting all day increases dementia risk — even if you exercise

https://www.washingtonpost.com/wellness/2023/09/27/sitting-sedentary-exercise-dementia/ Interesting article, and not good news if you have a sit-down desk job. I get help from my Apple watch which vibrates if I have been sitting an hour straight, telling me to get off my butt. And most of the time I...
by Fc1345linville
Fri Jul 07, 2023 8:01 am
Forum: Prevention and Treatment
Topic: Lecanemab full Approval!!!
Replies: 8
Views: 1034

Re: Lecanemab full Approval!!!

This Washington Post article on this is attached at the bottom. Here is a snippit that this group should definitely read: "The FDA said the drug’s label will include a “boxed warning” highlighting safety issues. That warning, sometimes called a “black box,” says that Leqembi, and other members ...
by Fc1345linville
Sun Jul 02, 2023 9:04 am
Forum: Announcements and Events
Topic: Gene Therapy Trial for ApoE4 Homozygotes
Replies: 49
Views: 37673

Re: Gene Therapy Trial for ApoE4 Homozygotes

Great idea. The Trial is still open, accepting new participants, so where is there a better source of candidates than here?
by Fc1345linville
Sat Jun 10, 2023 11:18 am
Forum: Prevention and Treatment
Topic: FDA Advisory Panel Unanimously Recommends Lecanemab
Replies: 12
Views: 1444

Re: FDA Advisory Panel Unanimously Recommends Lecanemab

At a $26,000 per year cost to Medicare for Lecanemab, drug companies are definitely disincentivised to find cures, which would kill their golden goose annuity. Another example of treat-don't-cure is that insulin keeps millions of diabetics alive, and the price of insulin tripled in the past 10 years...
by Fc1345linville
Thu Dec 29, 2022 2:32 pm
Forum: Prevention and Treatment
Topic: Celebration Thread! Biogen is going to the FDA with Aducan.
Replies: 1808
Views: 346215

Re: Celebration Thread! Biogen is going to the FDA with Aducan.

"House Investigation faults FDA and Biogen forAlzheimer's Drug Approval" Dec. 29 at 1;52PM

Lock 'em Up.


https://mail.google.com/mail/u/0/#inbox ... XdXSfFvTDs
by Fc1345linville
Mon Nov 28, 2022 11:12 am
Forum: Our Stories
Topic: Hello from an Assisted Living Homeowner
Replies: 7
Views: 810

Re: Hello from an Assisted Living Homeowner

I am not familiar with Marama, but after eight years as a Volunteer Ombudsman at three different large Assisted Living Facilities, all of which include "memory units", residents diagnosed with dementia always live in secure environments. Numerical codes to open doors and elevators. The Sta...
by Fc1345linville
Tue Oct 18, 2022 2:38 pm
Forum: Science and Research
Topic: Exercise as Top Treatment
Replies: 2
Views: 684

Re: Exercise as Top Treatment

Good to hear this, Plumster! Many of you probably are tired of hearing this, but I am an 80 yr old 4/4 who has been exercising for an hour or more almost every day for the last 50 years. I get eight hours of sleep, have a healthy diet, and perhaps most importantly, I enjoy every aspect of those rout...
by Fc1345linville
Tue Mar 01, 2022 10:49 am
Forum: Science and Research
Topic: APOE genotyping: more complex than my old 23andme summary suggested
Replies: 17
Views: 2032

Re: APOE genotyping: more complex than my old 23andme summary suggested

Yes, Dr. Michael Greicius of Stanford is the Neurologist that got me into the study in 2015-16, and I am still in it. I think a Dr. Henderson is now running this particular study.

Fc