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by apod
Mon Nov 25, 2019 8:38 pm
Forum: Science and Research
Topic: A Moderate-Fat Diet with One Avocado per Day Increases Plasma Antioxidants and Decreases the Oxidation of sdLDL
Replies: 0
Views: 495

A Moderate-Fat Diet with One Avocado per Day Increases Plasma Antioxidants and Decreases the Oxidation of sdLDL

A Moderate-Fat Diet with One Avocado per Day Increases Plasma Antioxidants and Decreases the Oxidation of Small, Dense LDL in Adults with Overweight and Obesity: A Randomized Controlled Trial (The Journal of Nutrition 2019): https://academic.oup.com/jn/advance-article/doi/10.1093/jn/nxz231/5588100 ...
by apod
Mon Nov 18, 2019 2:23 pm
Forum: Science and Research
Topic: Plasmalogens- exciting new evidence
Replies: 142
Views: 30840

Re: Plasmalogens- exciting new evidence

Hi everyone, Excellent questions. The metabolic precursor to the blood and membrane plasmalogens (the vinyl ether phospholipid form) is the 1-O-alkyl, 2-acyl glycerol (free hydroxy at sn-3). Detailed structure activity of modulating specific plasmalogen species using specific alkyl-acyl glycerols i...
by apod
Sun Nov 17, 2019 12:05 am
Forum: Science and Research
Topic: Plasmalogens- exciting new evidence
Replies: 142
Views: 30840

Re: Plasmalogens- exciting new evidence

Another curious window shopper here as well. If I'm reading this right, the supplement would also provide .6g of omega-3 (phospholipid bound?) The E4 allele seems to have a much better time taking up DHA from phospholipids than TG/EE forms. This could be a very nice combo just for that bioavailable ...
by apod
Sat Nov 16, 2019 10:34 am
Forum: Prevention and Treatment
Topic: Epigenetic tracking with Elysium Index
Replies: 2
Views: 568

Re: Epigenetic tracking with Elysium Index

You don’t need to wait until January this test already exists by a company that David Sinclair invested in called Inner age https://www.insidetracker.com/innerage/ This new test directly measures epigenetic biomarkers (like the ones Sinclair references in his latest book) looking at DNA methylation...
by apod
Fri Nov 15, 2019 10:56 pm
Forum: Prevention and Treatment
Topic: Tracking HRV
Replies: 1
Views: 435

Re: Tracking HRV

I track my HRV regularly using the Oura ring too. I'd love to find some correlations for improving that number. Lately, I've been on a bit of a downtrend, not prioritizing sleep. Another metric I like is PWV. I used to get this off my Withings Scale (Body Cardio), but they removed the feature after ...
by apod
Thu Nov 14, 2019 9:51 am
Forum: Prevention and Treatment
Topic: Epigenetic tracking with Elysium Index
Replies: 2
Views: 568

Epigenetic tracking with Elysium Index

This new test from Elysium looks pretty cool: https://www.elysiumhealth.com/en-us/index "How fast have you been aging? We all age at different cumulative rates. Start tracking yours with Index in January 2020." "Index is powered by the Elysium chip, developed with the help of a global...
by apod
Thu Sep 26, 2019 6:49 pm
Forum: Science and Research
Topic: Thiamin and protein folding
Replies: 10
Views: 1234

Re: Thiamin and protein folding

I've gone back and forth on B1 supplementation myself. I've read that polyphenols lower B1 and low-carb diets tend to be lower in B1. So, I think it makes a lot of sense on paper. What are the thoughts on TKL1 activation and potential cancer risk?
by apod
Mon Sep 09, 2019 1:49 pm
Forum: Our Stories
Topic: Two month N=1 experiment plus questions: 250 mg NMN + 50 mg pterostilbene
Replies: 14
Views: 1671

Re: Two month N=1 experiment plus questions: 250 mg NMN + 50 mg pterostilbene

Very interesting data. I've been hesitant to try pterostilbene as I've read that it has a negative effect on lipids / LDL. It doesn't look like this was the case in your experiment.
by apod
Sun Sep 08, 2019 12:33 am
Forum: Prevention and Treatment
Topic: New Book about Fasting, Exercising, reprogramming cells
Replies: 6
Views: 1111

Re: New Book about Fasting, Exercising, reprogramming cells

I've got my Audible credit at the ready! Now, when do we get to read Peter Attia's thoughts on similar matters?
by apod
Sun Sep 08, 2019 12:29 am
Forum: Science and Research
Topic: How TMAO Fooled Us
Replies: 19
Views: 2284

Re: How TMAO Fooled Us

I find the articles on TMAO feeding to promote cardiovascular disease somewhat convincing. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300890/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943035/ It doesn't seem so much like an unhealthy diet or kidney disease happens to be associated with this T...

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