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by sabaka
Tue Oct 22, 2019 3:37 pm
Forum: Science and Research
Topic: halting Phase III trials of aducanumab
Replies: 17
Views: 2520

Re: halting Phase III trials of aducanumab

I wonder if there is any data comparing the results for the Apoe4 and the non-carriers. I can't find any so far. Based on the Biogen website, 2/3 of participants were Apoe4 carriers. Apoe4 carriers were initially titrated to 6mg/kg (low dose of non-carriers) and only later were titrated to 10 mg/kg...
by sabaka
Thu Jul 25, 2019 11:28 am
Forum: Prevention and Treatment
Topic: Question about supplements and endalznow.org
Replies: 8
Views: 1352

Re: Question about supplements and endalznow.org

Thank you everyone for your input!
BrianR, Fiver, xactly, apod, floramaria, slacker ,
thank you.
by sabaka
Wed Jul 17, 2019 7:04 pm
Forum: Prevention and Treatment
Topic: Question about supplements and endalznow.org
Replies: 8
Views: 1352

Re: Question about supplements and endalznow.org

Thank you very much for your responses! My genetic counselor told "amyloid is building up in your brain ". I bought krill oil, turmeric, and some other supplements all based on the overwhelming advice from the internet. Huge bottles with many pills from Costco. My blood work is fine except...
by sabaka
Wed Jul 17, 2019 10:16 am
Forum: Prevention and Treatment
Topic: Question about supplements and endalznow.org
Replies: 8
Views: 1352

Question about supplements and endalznow.org

Received an email from Alzheimer's Prevention Registry saying "no" to supplements for brain health. Am I reading this right? I thought there was scientific evidence that Tumeric, krill oil and some other supplements are beneficial for the brain. GCBH examined evidence available about vitam...
by sabaka
Wed Apr 17, 2019 9:56 am
Forum: Prevention and Treatment
Topic: Worry impacts differently ApoE-ε4 Carriers and Non-Carriers
Replies: 0
Views: 332

Worry impacts differently ApoE-ε4 Carriers and Non-Carriers

I came across this article today: Effect of Worry Level on Recall Memory for Odors in ApoE-ε4 Carriers and Non-Carriers. https://www.ncbi.nlm.nih.gov/pubmed/30987686 The main finding is that A significant interaction effect between ε4 status and worry on both short-and long-delay cued recall was fou...
by sabaka
Thu Apr 04, 2019 10:42 am
Forum: Our Stories
Topic: New e4/e4
Replies: 14
Views: 2011

Re: New e4/e4

Anna wrote: The CBD seems to affect how deeply I sleep.

What kind of CBD are you using? I want to try, heard a few good stories about it.
by sabaka
Thu Apr 04, 2019 10:11 am
Forum: Our Stories
Topic: New e4/e4
Replies: 14
Views: 2011

Re: New e4/e4

I celebrate when I hit 7 hours (especially consecutive) Yes, it was my goal too: get two 7 hr sleeps in a row. I lowered the threshold by 30 min after I read a study by FitBit, https://blog.fitbit.com/sleep-study/ , the takeaway is that for women age > 55 average sleep time is around 6.5 hours. The...
by sabaka
Wed Apr 03, 2019 11:41 am
Forum: Our Stories
Topic: New e4/e4
Replies: 14
Views: 2011

Re: New e4/e4

Thank you, Anna! Not an easy journey so far. I am intimately familiar with the misery of chronic sleep deprivation resulting from relentless insomnia. I am not sure if you are aware that the anticholinergic effects of some drugs, including the antihistamines in Unisom, are linked to dementia. This i...
by sabaka
Tue Apr 02, 2019 5:01 pm
Forum: Our Stories
Topic: New e4/e4
Replies: 14
Views: 2011

Re: New e4/e4

Hi Sabaka....thanks for joining up. Can you tell us a bit more about what the fitbit Charge tracker tells you? Specifically, is it in any way a possible substitute for the at-home sleep apnea testing? Hi Sue, Fitbit tracks your heart rate and movements during the day. Based on this data fitbit is a...
by sabaka
Tue Apr 02, 2019 11:15 am
Forum: Meet-Ups
Topic: Any NORCAL folks interested in a get together?
Replies: 121
Views: 12842

Re: Any NORCAL folks interested in a get together?

I want to come but it is a little too far. Any chance someone is driving from San Mateo?

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