Search found 56 matches

by antimatter37
Mon Feb 05, 2024 4:39 pm
Forum: Prevention and Treatment
Topic: NAD
Replies: 3
Views: 472

Re: NAD

Here is a link to a brief discussion of NAD on this forum.

viewtopic.php?p=53950#p53950
by antimatter37
Thu Dec 14, 2023 10:59 am
Forum: Prevention and Treatment
Topic: Increasing BDNF
Replies: 1
Views: 9710

Increasing BDNF

Many research groups familiar to folks on this site have mentioned brain derived neurotropic factor (BDNF) as a very important factor in overall brain health, especially as we age. Here is a free PDF from Dr. Rhonda Patrick that helps describe a number of ways we can increase our levels of BDNF. The...
by antimatter37
Sun Oct 22, 2023 3:45 pm
Forum: Prevention and Treatment
Topic: I Can Hardly” Believe It Viagra Reduces Alz Risk
Replies: 25
Views: 6001

Re: I Can Hardly” Believe It Viagra Reduces Alz Risk

From a research group at Mt Sinai using a large data-based analysis of over 50k individuals: "The propensity score stratified univariate analysis and the Cox regression model showed that sildenafil use was significantly associated with a 60% risk reduction of developing Alzheimer's disease (HR=...
by antimatter37
Tue Sep 05, 2023 5:50 pm
Forum: Science and Research
Topic: Homotaurine (tramiprosate) appears to be a structure corrector
Replies: 77
Views: 131270

Re: Homotaurine (tramiprosate) appears to be a structure corrector

Is anyone aware of a comparison of homotaurine with the garden variety taurine? There are many, many articles published in the scientific literature on the benefits of taurine for the brain. Taurine Sci Rep.pdf Taurine Nature.pdf Plain old taurine may also show some benefits for longevity (many arti...
by antimatter37
Thu Jan 26, 2023 9:16 am
Forum: Prevention and Treatment
Topic: ACI-24.060
Replies: 0
Views: 420

ACI-24.060

Interesting phase1/2 result. AC Immune's "vaccine" ACI-24.060 has showed positive results and initial safety at low doses. The trial is now moving to higher doses. The drug is a liposome vaccine that stimulates one's own body to produce amyloid beta antibodies and subsequently clear the pl...
by antimatter37
Fri Apr 01, 2022 4:07 pm
Forum: Science and Research
Topic: ALZ-801, tramiprosate, Ptau-181
Replies: 11
Views: 1882

Re: ALZ-801, tramiprosate, Ptau-181

Thanks all. I will also continue my 2 per week 100 mg of homotaurine.
by antimatter37
Thu Mar 31, 2022 1:51 pm
Forum: Science and Research
Topic: ALZ-801, tramiprosate, Ptau-181
Replies: 11
Views: 1882

Re: ALZ-801, tramiprosate, Ptau-181

Thanks all for these updates. I believe that tramiprosate is simply homotaurine (is this correct?) Homotaurine is the amino acid taurine with an additional carbon atom attached. You can purchase it inexpensively on the web: https://us.supersmart.com/en/shop/brain-nutrition/homotaurine-supplement-066...
by antimatter37
Sun Feb 20, 2022 10:26 am
Forum: Prevention and Treatment
Topic: You CAN Turn Back Time
Replies: 5
Views: 1943

Re: You CAN Turn Back Time

For those interested in "life extension" overall, as well as its relationship to cognitive decline, here are a few recent podcasts from David Sinclair at Harvard Medical School: https://www.youtube.com/watch?v=X1kLizzdb2c https://www.youtube.com/watch?v=wD8reCw3Kls https://www.youtube.com/...
by antimatter37
Fri Dec 10, 2021 8:35 am
Forum: Science and Research
Topic: Microglial correlates of late life physical activity
Replies: 2
Views: 690

Re: Microglial correlates of late life physical activity

Here is an interesting article from Harvard Medicine on "Inflammation and Brain Health" that correlates to this discussion on using exercise to reduce brain inflammation.

https://hms.harvard.edu/magazine/aging/ ... ain-health