The stories are all very similar. I remember how relieved I was when I finally discovered the cause was a side effect from melatonin supplements. I know that it is a naturally occurring hormone, but taking it orally must be the issue. And I have no idea what the incidence of this side effect is, but...

Benson, I do not remember stomach growling as a significant part of my symptoms. My experience was relentless, persistent watery diarrhea, worse in the morning. No fever, no pain. The original article said it could take up to six weeks. Mountaineermd.

I suspect that it is melatonin itself that causes the watery diarrhea. I have take magnesium supplements without any diarrhea, yet my melatonin experience led me to initiate the experience on this site. I happen to be Apoe3/4, but I doubt there is any relation to ones Apoe status.

Trevor, Finding out that you are 4/4 is your wake up call to start living a healthy life style. Alzheimers is a disease of modern civilization, highly correlated with refined sugars, flour and seed oils. You may have a genetic risk, but you can significantly minimize that risk thru epigenetics. In a...

Danagalmc, Hang in there. it can take up to six weeks to completely resolve, but usually it resolves sooner.

I also believe suppressing mTor is an important step for healthy aging. I am a 70 yo retired physician with one copy of ApoE4. I practice daily time restricted eating, usually 18:6. I have recently began doing longer fasts to really kick start autophagy. (my record is 84 hours). I recommend The Swit...

It is rewarding for me to see that so many people have benefited from this post. Relentless watery diarrhea is no fun and who would have guesses it was caused by melatonin.

Shiro, I posted my experience with persistent watery diarrhea related to melatonin, hoping it would be read by others with the same issue. I am happy to read that your wife discovered the post and you are now cured. Robert Johnson MD, mountaineermd.

I had been taken 1 or 2 mg of melatonin at bed time for about 5 or 6 weeks. The diarrhea was worse in the morning, The web site I discovered was HealingWell.com, search melatonin and diarrhea. I must admit, melatonin was the last thing I would have thought would cause diarrhea. And since it took abo...

I posted this in hopes of providing useful information for those who suffer from persistent watery diarrhea. Many of the people who where relating their experience, had undergone stool cultures, colonoscopy, biopsy, and treatment for irritable bowel syndrome. IF you are taking melatonin and develop ...