Darn, no one has responded! I thought this was a great question and really wanted to read what someone with direct knowledge would say. We do emphasize hormonal balance for ApoE4s. Absolutely! In general, when many of us think of hormones we think sex hormones, but there are so many more! Other imp...

I'm currently comparing birth control methods and am looking for any insight into how hormonal options might affect cognitive (and general) health. I've heard that some functional practitioners don't want their patients on hormonal contraception at all, but I don't have the background to evaluate wh...

My own experience has been that I needed to adjust folate down as I added other methylation support. With that much creatine and PC, you might be ending up with excess SAMe from folate, because creatine and PC are reducing the need for the folate/SAMe in supplying the major methyltransferases PEMT ...

I don't know the amounts of each you are taking, but excess folate can certainly lead to insomnia, and most likely your elevated heart rate. I'd back that off first and see where you land on your symptoms. Thanks for the quick response. The methyl folate is 800 mcg, the B12 is 1000 mcg, the P5P is ...

Due to my wacky genes, I currently take a bunch of supplements for methylation (methyl folate, B12, P5P, creatine and phosphatidylcholine). Although I'm 26 and in good shape, my homocysteine was once very high, which was what motivated me to start supplementing. I have a suspicion that I might be ov...

I concur! I've used mine for over a year now and I absolutely love it. I'm considering purchasing one. Some reviewers on Amazon claimed that the machine was quite sensitive and that all the components needed to align in order for it to function properly. Has that been your experience too? Hi Rainbo...

Plumster wrote:I concur! I've used mine for over a year now and I absolutely love it.

I'm considering purchasing one. Some reviewers on Amazon claimed that the machine was quite sensitive and that all the components needed to align in order for it to function properly. Has that been your experience too?

Hi all, I'm a new 4/4 member to this site. I'm a 36yo scientist with experience in theoretical (astro)physics and data science. Lately I got totally obsessed with my new found interest in health, longevity, and this ApoE thing all of us here have going on. I've learned a lot already, but I realize ...

If you are willing to be quoted (anonymously or not) I’m looking for comments on -how you found out - how you felt - whether this group or any others have been supportive -if you’ve changed your lifestyle as a result Hi Flora, I'm a twenty-five-year-old and 4/4. I'm also interested to know more abo...

Hello, I am new here so I apologize if I break any site rules. I just recently found out that I am 4/4 and I am very scared. Finding out at this age gives me lots of time for prevention, right? Someone please offer me some advice - I feel as if I have rec'd a death sentence. Hi there and welcome to...