Our 3rd annual meet-up will piggyback on the LowCarb USA conference in San Diego, CA, August 3-6.

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by Gilgamesh
Fri Jun 23, 2017 11:14 am
Forum: Science and Research
Topic: High-fat diet leads to same intestinal inflammation as a virus
Replies: 10
Views: 242

Re: High-fat diet leads to same intestinal inflammation as a virus

apod, thanks for being far less lazy than I was this morning when I posted the link to the report on the study! The dietary constituents make it pretty clear that I can keep eating my mounds of nuts! :mrgreen: (Or rather: that this study provides no evidence to make me stop.) The tomato compound is ...
by Gilgamesh
Fri Jun 23, 2017 5:55 am
Forum: Science and Research
Topic: High-fat diet leads to same intestinal inflammation as a virus
Replies: 10
Views: 242

High-fat diet leads to same intestinal inflammation as a virus

https://medicalxpress.com/news/2017-06-high-fat-diet-intestinal-inflammation-virus.html

Will have to read the study to see what kind of fat it was, of course (and whether there was any bodyweight change).
by Gilgamesh
Wed Jun 21, 2017 11:47 am
Forum: Announcements and Events
Topic: Head count for our 2017 meet-up
Replies: 17
Views: 393

Re: Head count for our 2017 meet-up

I am, and feel like, such such a zero in this headcount! Really wish I could be there. Will be there in epsilon-4 spirit! xo
by Gilgamesh
Wed Jun 21, 2017 11:10 am
Forum: Science and Research
Topic: Designing an E4 Fasting trial...
Replies: 71
Views: 2792

Re: Designing an E4 Fasting trial...

Humans may need to go significantly longer than rodents for the same "signal". I think that could be right, but it may depend on the signal in question . The interesting CR Society discussion (previous link) makes me wonder whether more frequent two-day fasts might be optimal for many (ag...
by Gilgamesh
Sun Jun 18, 2017 8:11 am
Forum: Science and Research
Topic: Designing an E4 Fasting trial...
Replies: 71
Views: 2792

Re: Designing an E4 Fasting trial...

Wow, so you're fasting much more often than one would following Longo's protocol. Of course, his recommendations are influenced to a great degree but what he thinks would be doable by most people.

G
by Gilgamesh
Sun Jun 18, 2017 5:50 am
Forum: Science and Research
Topic: Designing an E4 Fasting trial...
Replies: 71
Views: 2792

Re: Designing an E4 Fasting trial...

GeorgeN wrote:Of course it was my 5th day of fasting on my 4th fasting/refeeding cycle
George, how long have you waited between fasting cycles?
by Gilgamesh
Sun Jun 18, 2017 5:48 am
Forum: Our Stories
Topic: Oxidized LDL (OxLDL) and Myeloperoxidase (MPO) test results
Replies: 16
Views: 584

Re: Oxidized LDL (OxLDL) and Myeloperoxidase (MPO) test results

Alysson, I'm sorry about your aunt. I recall seeing plenty of non-APOE-related SNPs at SNPedia linked to heart disease, but the mechanism almost always was argued to be cholesterol-mediated. To be honest, I reached a point a while back where I decided I'd take a break from SNP-surfing, and wait a ye...
by Gilgamesh
Sat Jun 17, 2017 5:20 am
Forum: Science and Research
Topic: Designing an E4 Fasting trial...
Replies: 71
Views: 2792

Re: Designing an E4 Fasting trial...

Wow, George, amazing! You rock!
by Gilgamesh
Fri Jun 16, 2017 4:44 am
Forum: Science and Research
Topic: Designing an E4 Fasting trial...
Replies: 71
Views: 2792

Re: Designing an E4 Fasting trial...

Hey apod. Yeah, I'm going to crank up the protein (and, a bit, carbs) for the next few days, and definitely emphasize resistance training (was doing that during the fast, actually). I'm still plowing through Longo's work. Uncertain about how to do the "immune-rebuilding" part of the diet. ...
by Gilgamesh
Thu Jun 15, 2017 4:04 pm
Forum: Our Stories
Topic: Oxidized LDL (OxLDL) and Myeloperoxidase (MPO) test results
Replies: 16
Views: 584

Re: Oxidized LDL (OxLDL) and Myeloperoxidase (MPO) test results

Yeah, this "minimal"/"mild" business is irritating! I just saw my doc, and he thinks, given my healthy lifestyle (though there have been non-brief extreme exceptions, which can do a lot of damage), it's probably the horrible vascular/heart health genes I got from my mom. The doc ...

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