Search found 5981 matches

Go to advanced search

by Julie G
Tue Feb 20, 2018 11:21 am
Forum: Prevention and Treatment
Topic: Quick question how to lower Homocysteine
Replies: 8
Views: 164

Re: Quick question how to lower Homocysteine

Good discussion. The wiki article is enormously dense as it reflects Susan's understanding on the topic ;). Deep bow. That said, I have a question re. the information as it's presented. My understanding is that B12, folate AND B6 (or the activated form, P5P) in the presence of a healthy Omega-3 inde...
by Julie G
Mon Feb 19, 2018 7:48 pm
Forum: Prevention and Treatment
Topic: best supplements for immediate short term memory??
Replies: 4
Views: 128

Re: best supplements for immediate short term memory??

Jeff, there's no easy answer. It depends on what's driving the memory issues. If you have a lot of inflammation, curcumin might be really helpful. (It's the one that helped me the most.) If it's high homocysteine, B12, folate & B6 may be the best. If its low Vitamin D, Vitamin D3 supplementation...
by Julie G
Sun Feb 18, 2018 11:55 am
Forum: Science and Research
Topic: Plasmalogens- exciting new evidence
Replies: 46
Views: 1027

Re: Plasmalogens- exciting new evidence

It is interesting to note from the slides that in the highest Pls1 group, the LDL and total cholesterol are also high as well, too. Yeah, Marc questioned that because Dayan asserted (despite his data) that low LDL was preferable. He cautioned us against literally applying the LDL/TC information pre...
by Julie G
Sun Feb 18, 2018 10:14 am
Forum: Science and Research
Topic: Plasmalogens- exciting new evidence
Replies: 46
Views: 1027

Re: Plasmalogens- exciting new evidence

So how can we check these levels? I note it is plasma levels as well, not levels in the brain...Would it relate to or be indicated by HDL / trigs ratio? Dayan (like Rasmussesn with APOE) is using plasma levels. The testing is not particularly difficult, but unfortunately not widely available. Once ...
by Julie G
Sun Feb 18, 2018 10:03 am
Forum: Science and Research
Topic: Plasmalogens- exciting new evidence
Replies: 46
Views: 1027

Re: Plasmalogens- exciting new evidence

It's hard for me to interpret slide #73 out of context. Maybe it would make more sense to me if I had heard the entire presentation as well as view the slides. I'm a mixed media audiovisual learner! I hear you. Maybe we can make that happen... Simply stated, plamalogen levels are fairly difficult t...
by Julie G
Sun Feb 18, 2018 7:58 am
Forum: Science and Research
Topic: Plasmalogens- exciting new evidence
Replies: 46
Views: 1027

Re: Plasmalogens- exciting new evidence

There appears to be an association between high HDL, low TGs, and high HDL/LDL ratio to high plasmalogen levels, but is there a causal relationship or merely an association? Correct. It's an association or correlation. Do we know that tinkering with these other lipid markers results in higher plasm...
by Julie G
Sat Feb 17, 2018 8:06 pm
Forum: Science and Research
Topic: Plasmalogens- exciting new evidence
Replies: 46
Views: 1027

Re: Plasmalogens- exciting new evidence

It was an honor to learn about Dayan's work. (Susan & George also attended the presentation.) I was struck by, and he confirmed, the close relationship between peripheral plasma APOE and plasmalogen. Remember Rasmussen's work? Because plasmalogen is a phospholipid, you'll note (Slide #73) the co...
by Julie G
Sat Feb 17, 2018 7:42 am
Forum: Science and Research
Topic: Htr-A1 - ApoE4 degrading enzyme
Replies: 21
Views: 1193

Re: Htr-A1 - ApoE4 degrading enzyme

Good morning, Orangeblossom! We've previously discussed Rasmussen's more recent paper. From her conclusions: The situation in the brain and in the periphery differs very much; lipids in the nervous system are necessary for normal function, whereas lipids in the periphery are associated with risk of ...
by Julie G
Fri Feb 16, 2018 2:33 pm
Forum: Science and Research
Topic: Genetic differences & Alzheimer's disease
Replies: 10
Views: 353

Re: Genetic differences & Alzheimer's disease

So, when large-scale studies show benefits from an intervention (eg., green leafy vegetables improve well-being in many ways), then the unfavorable N=1 outcomes or adverse effects in an individual (eg., too frequent bowel movements) don't overturn the findings of the large-scale study for others. B...
by Julie G
Fri Feb 16, 2018 9:59 am
Forum: Science and Research
Topic: Genetic differences & Alzheimer's disease
Replies: 10
Views: 353

Re: Genetic differences & Alzheimer's disease

For example, a study involving 10,000 women who are APOE4 homozygous carriers is likely to be more applicable to you than a study involving only one such carrier. That's because you're more likely to be like the average of the 10,000 women, genome-wise, than like the one individual woman - unless t...

Go to advanced search