If you have children who grow up to be like any of the wonderful people on this site you will have given us all a gift. The genetic information you have will inform many choices--you may want to steer those kids away from football and boxing careers and I expect they will be active and eat lots of v...

I will probably wait as well, Circular. I expect most of us who carry an ApoE4 will have at least some amyloid. In fact, it would be interesting to see the results of that test on a hundred or so 65yr old or more asymptomatic folk carrying 1 or 2 copies of the gene.

Does anyone know the price for the new PrecivityAD blood test for amyloid & risk?

You would benefit by getting a followup scan with and without contrast to compare to this one. I am not sure if the time interval would be 6 or 12 months, that would depend on your symptoms. You would be looking for changes over time that would suggest a diagnosis or a need for additional tests. A s...

I only have one on my MRI. I have a history of migraines, a family history full of early cardiac deaths,high lipids and a heart like a stone. You can see those white matter abnormalities with classic migraines, diabetes, hypertension, and sometimes lots of them without symptoms. Just like any other ...

There are many potential causes for Pseudobulbar affect--the uncontrollable tearing up or laughing in excess of what your usual emotional response would have been. Lists of causes, workups, treatments (mainstream and complimentary) and support groups abound if you google that topic. Some causes are ...

Hi all, Sorry for a bit of a rant here, but I think it is very important to make sure that the site from which you share an article to the public does not represent extreme or antiscience views on other topics even if the referred article does not include such issues. Today's posting on FB shared a ...

The rs2303697 minor (T) allele was protective in all cohorts except for CHARGE (eTable 3, eFigure 3B in the Supplement). In the discovery sample, the interaction between rs2303697 and APOE ε4 status was significant (interaction P = 3.88 × 10−5) (eTable 2 in the Supplement), and the T allele showed a...

Hey NotSure--the goal was never forever-----fortunately a lot of the things we are supposed to do to delay the disability are enjoyable. So dance, dream (with excellent sleep), slurp mussels and saute morels, take a sip of red wine as you recite poems in Spanish to friends and family and train that ...

"prevalence of dementia in APOE ε3ε4/ε4ε4 persons with high PBV values (>1 SD from mean) was observed to be the same as APOE ε3ε3 persons (14.3% versus 14.0%). " Looks like I will eat mussels and egg yolks a little more frequently while waiting to find out if we can impact our own levels w...