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by SusanJ
Fri May 15, 2020 6:51 am
Forum: Prevention and Treatment
Topic: PREPRINT: Increased risk from COVI-19 in apoe4s
Replies: 9
Views: 499

Re: PREPRINT: Increased risk from COVI-19 in apoe4s

My mom died of probable covid last month. So sorry to hear about your mom, and sending some virtual hugs your way. There are so many challenges to keeping LTC folks safe. My SIL's father, age 92 in a LTC facility, died 2 weeks ago of Covid-19 (he was tested when he got symptoms). Seemed to be getti...
by SusanJ
Mon May 04, 2020 10:12 am
Forum: Science and Research
Topic: Alzheimer's Afternoons Seminar Series Summaries
Replies: 17
Views: 1051

Re: Alzheimer's Afternoons Seminar Series Summaries

Fiver wrote:Alzheimer’s Afternoon Seminar Series


Thanks again for the summaries.

Dr. Macauley's and Dr. Zuloaga’s research made me think of how we used to call dementia, hardening of the arteries.
by SusanJ
Mon May 04, 2020 10:03 am
Forum: Science and Research
Topic: Apoe4 leads to BBB disfunction
Replies: 3
Views: 352

Re: Apoe4 leads to BBB disfunction

I wonder what are the consequences for us? This overview article , posted on our Facebook page, has a section on ApoE4 and the BBB. A culmination of these studies implicates ApoE4 in decreasing BBB integrity through weakening tight junctions, increases in MMP9 and a loss of support needed for the B...
by SusanJ
Fri Apr 24, 2020 6:08 am
Forum: Our Stories
Topic: 4/4 and both parents
Replies: 7
Views: 778

Re: 4/4 and both parents

How are other people getting sufficient amounts, in the correct form of EPA and DHA? Welcome. We've had several discussions about this. I did a search and several threads come up that you might want to explore. I just put "phospholipids fish oil" in the search box and got these results . ...
by SusanJ
Wed Apr 22, 2020 7:19 am
Forum: Science and Research
Topic: Amyloid beta plaques might develop due to low levels of CIB1
Replies: 0
Views: 219

Amyloid beta plaques might develop due to low levels of CIB1

New research out of Japan. Might be one to watch. Researchers tested a total of 19,150 individual genes for their effect on amyloid beta levels and ruled out all but one: calcium and integrin-binding protein 1 (CIB1). Cells without functional CIB1 genes produced abnormally high levels of amyloid bet...
by SusanJ
Mon Apr 20, 2020 9:12 am
Forum: Science and Research
Topic: KLOTHO: Good news for 20% of us!
Replies: 11
Views: 1249

Re: KLOTHO: Good news for 20% of us!

So I went to Promethease and followed their link to Snpedia. Here's what they have to say about this combo: rs9536314, also known as c.1062T>G, p.Phe352Val and F352V, represents a variant in the KL (Klotho) gene on chromosome 13. Together with rs9527025 (C370S), which it co-segregates with, a haplot...
by SusanJ
Sat Apr 18, 2020 8:32 am
Forum: Science and Research
Topic: Some Animals Have No Microbiome. Here’s What That Tells Us.
Replies: 0
Views: 177

Some Animals Have No Microbiome. Here’s What That Tells Us.

Fascinating article for those of us watching microbiome research. Regardless, the findings illustrate that there’s much to learn by comparing species — and that there’s much to lose by making premature assumptions about what their relationships with bacteria might look like. At the very least, this ...
by SusanJ
Sat Apr 18, 2020 8:24 am
Forum: Our Stories
Topic: Question about Supplement Brands
Replies: 17
Views: 1095

Re: Question about Supplement Brands

Amberb wrote:Is there a way to tell the difference?


Don't know a reliable way. Some people complain about capsules being stuck together, smelling funny, looking different, etc. I think if you buy directly from the manufacturer through Amazon and not a third party then it's probably okay.
by SusanJ
Sat Apr 18, 2020 5:44 am
Forum: Science and Research
Topic: Alzheimer's Afternoons Seminar Series Summaries
Replies: 17
Views: 1051

Re: Alzheimer's Afternoons Seminar Series Summaries

Fiver, many thanks for taking the time to summarize and share these seminars! Much appreciation for these perspectives. Most studies struggle to find enough human 4/4 carries for studies and, as a result, group 4/4s and the more common 3/4s together as “apoe4 carriers”, a shortcut bound to muddy the...
by SusanJ
Wed Apr 15, 2020 2:59 pm
Forum: Our Stories
Topic: Question about Supplement Brands
Replies: 17
Views: 1095

Re: Question about Supplement Brands

Interesting, would Iherb be considered a trusted vitamin site? They provide a very good service for non USA customers. I've used iHerb in the past. I think others here have also used them. For what I buy now, I mostly use Pure Formulas because they have what I take in stock. I've read complaints ab...

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