Did anybody have success with lowering LDL (drastically) with other means or supplements? I'm a work in progress, but the doctor I'm currently working with says he sees LDL numbers drop once you fix underlying inflammation (usually infections like virus, Lyme, gut dysbiosis). He runs a practice tha...

I'm hoping maybe someone here can shed some light on what they've experienced with having the MTHFR mutation and the 4/4. I know we are all genetically different beyond those two genetic issues, but, I'm looking for some other ideas as to what may or may have not worked for others. Welcome, and alt...

In mouse models, they find that ε3s get few if any of the benefits of rapa that ε4/ε4s do, and actually impairs their brain glucose metabolism, though they did get some cognitive benefit and lower anxiety Thanks for this. Definitely something to watch. As a 3/4 I do see some things that help 4/4s t...

I'm ready to just go without supplements , but I did before I switched to a ketoflex and it jumped to 12.1 At your original reading of 7, were you taking the niacin? Because your homocysteine rise is likely related to the niacin. Your body gets rid of excess niacin by using up methyl groups. So tho...

Theracumin by whom? I am taking Vital Nutrients Curcumin which I sprinkle on food or just take and Simple Organics Tumeric for cooking. Regarding heavy metals Med Caps DPO arsenic detox and S-Acetyl Glutathione by whom? MedCaps DPO is a Xymogen product. As far as I know you can only get those throu...

Still can't find, and maybe there isn't best bioavailable supplements to help all over as well as brain and crossing blood-brain barrier. Not exactly sure if this is the answer for you, but I take Theracumin for brain health and overall inflammation reduction, along with fish oil. As far as heavy m...

While I wouldn't recommend the bariatric surgery option, this one shows Type 2 Diabetes can be reversed in a week on a hypo caloric diet. To test this hypothesis, a group of people with type 2 diabetes were studied before and during a 600 kcal/day diet (21). Within 7 days, liver fat decreased by 30%...

I'm sure you already know about the Krauss paper (Faghihina, Krauss 2012) indicating a high SFA diet leads to higher ApoC3 content in LDL particles vs. a lower SFA diet. Missed that one. Thanks for the reference. Saturated fat does bad things to my lipids, so I'm definitely interested in reading th...

The study posited that "rapidly consuming large quantities of food can be ecologically beneficial" in the wild, since, when coupled with slow stomach emptying rates, it could decrease the number of times needed to hunt or acquire food. Human stomach plasticity, according to the results of...

I read about this yesterday and found the HDL and apoC3 level connection interesting.

Here's the full text for the Koch research related to cognitive effects and their earlier work on the apoE, HDL and apoC3 connection.