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by DoubleBond
Thu Sep 10, 2020 10:38 am
Forum: Prevention and Treatment
Topic: Does Black Coffee Break a Fast?
Replies: 9
Views: 657

Re: Does Black Coffee Break a Fast?

Very interesting info, thanks Tincup and floramaria. There is also an interesting recent video from Dr. Nadir Ali presenting arguments that caffeine increases fat burning: https://www.youtube.com/watch?v=gqKW3FJr6ps&t=615s&ab_channel=nadirmirali and also that fasting + caffeine + exercise is...
by DoubleBond
Thu Sep 10, 2020 10:20 am
Forum: Prevention and Treatment
Topic: Celebration Thread! Homotaurine/Tramiprosate supplement
Replies: 32
Views: 1562

Re: Celebration Thread! Homotaurine/Tramiprosate supplement

I don't see much effect on BP from taurine 2g am and pm. We have been taking it for about 3 months. I found out that there was "A Randomized, Double-blind, Placebo-Controlled Clinical Trial Comparing Effects of Taurine Supplementation on Cognitive Function in Patients With Diabetes" https:...
by DoubleBond
Wed Sep 09, 2020 9:26 am
Forum: Prevention and Treatment
Topic: Celebration Thread! Homotaurine/Tramiprosate supplement
Replies: 32
Views: 1562

Re: Celebration Thread! Homotaurine/Tramiprosate supplement

rrmolo, that's very interesting - how much taurine have you been taking, and for how long?

Me and my wife are taking 2g x 2 daily. Thinking now about adding homotaurine.
by DoubleBond
Sat Aug 29, 2020 7:58 pm
Forum: Prevention and Treatment
Topic: Celebration Thread! Homotaurine/Tramiprosate supplement
Replies: 32
Views: 1562

Re: Celebration Thread! Homotaurine/Tramiprosate supplement

Thanks, J11! This thread reads now like a reference for all things homotaurine.

I think I am going to give it a try, even before it is approved by the FDA .
by DoubleBond
Sat Aug 29, 2020 2:09 pm
Forum: Prevention and Treatment
Topic: Celebration Thread! Homotaurine/Tramiprosate supplement
Replies: 32
Views: 1562

Re: Celebration Thread! Homotaurine/Tramiprosate supplement

Thanks for the reply, J11. Very encouraging. I can imagine that the big pharma companies are not very interested in testing the inexpensive, unpatentable products such as homotaurine or methylene blue. Do you happen to know why homotaurine is not being sold by US supplement producers? The only distr...
by DoubleBond
Sat Aug 29, 2020 12:59 pm
Forum: Prevention and Treatment
Topic: Celebration Thread! Homotaurine/Tramiprosate supplement
Replies: 32
Views: 1562

Re: Celebration Thread! Homotaurine/Tramiprosate supplement

That's really very exciting, J11,! Thanks for posting it. Immediately, questions come to my mind: 1) The dose used was 150 mg twice per day, i.e. 300 mg per day. I see at least one commercially available homotaurine supplement: https://us.supersmart.com/article.pl?id=0661 It costs $17 per 3,000 mg, ...
by DoubleBond
Wed Jul 22, 2020 3:05 pm
Forum: Science and Research
Topic: New paper from Dr. Gundry on stopping progression of CAD
Replies: 67
Views: 17057

Re: New paper from Dr. Gundry on stopping progression of CAD

Thanks, Tincup and GordonE - very helpful responses! For the last 2 years, I and my wife have been staying clear of grains, legumes, meat, and cheese, but eating lots of SMASH fish, omega-3 eggs, nuts, olive oil, and lots of veggies (including the lectin-loaded peppers and eggplants). Even though no...
by DoubleBond
Wed Jul 22, 2020 1:26 pm
Forum: Science and Research
Topic: New paper from Dr. Gundry on stopping progression of CAD
Replies: 67
Views: 17057

Re: New paper from Dr. Gundry on stopping progression of CAD

Lectins are one thing, fish and eggs are another. From the abstract: All Apo E 4 genotypes avoided animal fats and cheeses. If I understand correctly, this means no fatty fish (SMASH), mussels, eggs. So basically no dietary sources of DHA and EPA. Why this limitation? Does Gundry think that for APOE...
by DoubleBond
Tue Jul 21, 2020 2:27 pm
Forum: Science and Research
Topic: Dr. Rhonda: Get some DHA in phospholipid form
Replies: 80
Views: 20611

Re: Dr. Rhonda: Get some DHA in phospholipid form

New paper by a group from the Keck School of Medicine shows that daily supplementation of 2g DHA in triglyceride form increases DHA in the brains of APOE4's - just not as much as for APOE3's: https://pubmed.ncbi.nlm.nih.gov/32690472/ Here is the Abstract: Background: Past clinical trials of docosahe...
by DoubleBond
Wed Jun 24, 2020 3:10 pm
Forum: Science and Research
Topic: Healthy lifestyle and the risk of Alzheimer dementia
Replies: 2
Views: 971

Re: Healthy lifestyle and the risk of Alzheimer dementia

Yes, the paper shows that healthy lifestyle benefits APOE4 too - not to the same degree as APOE3, but still quite substantially. In terms of hazard ratio HR for each of the 5 healthy behaviors: In the stratified analyses by the presence of the APOE e4 allele, the pooled HR among noncarriers was 0.68...

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