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by Jgreg80
Fri Aug 09, 2019 7:30 am
Forum: Science and Research
Topic: New ApoE4 protective SNPs
Replies: 8
Views: 1896

Re: New ApoE4 protective SNPs

Found the full article - https://www.researchgate.net/publication/333684488_Analysis_of_Whole-Exome_Sequencing_Data_for_Alzheimer_Disease_Stratified_by_APOE_Genotype The odds ratio for the minor T allele of rs2303697 is O.73. A 27% reduction in AD for us ApoE4’s, I’ll take it. Btw, It’s genotyped by...
by Jgreg80
Sat Jun 15, 2019 8:21 am
Forum: Science and Research
Topic: New ApoE4 protective SNPs
Replies: 8
Views: 1896

New ApoE4 protective SNPs

Hi all, came across this and figured I’d post it here https://www.alzforum.org/news/research-news/sliced-apoe-genotype-whole-exome-data-yield-new-ad-variants https://jamanetwork.com/journals/jamaneurology/article-abstract/2735123 The top ApoE4 protective SNP (ISYNA1, rs2303697) is genotyped by Ances...

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