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by circular
Tue Mar 23, 2021 7:16 am
Forum: Prevention and Treatment
Topic: BHRT talk with Bredesen, Hathaway and Julie G
Replies: 16
Views: 1026

Re: BHRT talk with Bredesen, Hathaway and Julie G

I know; I tried. I brought all of the questions to Dr. Hathaway's attention and we got the response that you've already seen- sorry. Thanks Julie. I think this matter of becoming progesterone resistant (not a medical term … yet?) may be very real. My levels were normal until suddenly they were too ...
by circular
Sun Mar 21, 2021 11:37 am
Forum: Prevention and Treatment
Topic: BHRT talk with Bredesen, Hathaway and Julie G
Replies: 16
Views: 1026

Re: BHRT talk with Bredesen, Hathaway and Julie G

Still wondering why estrogen doesn't ideally need to be cycled too. Interesting question. Would you consider posing it on FB so I can bring it to Dr. Hathaway's attention? FWIW, I've settled on a strange pattern of progesterone usage, suggested by my gyn. I use 100mg every other night because I hav...
by circular
Fri Mar 05, 2021 1:44 pm
Forum: Science and Research
Topic: Study: why the APOE4 gene enhances Alzheimer’s risk; choline reverses
Replies: 1
Views: 369

Re: Study: why the APOE4 gene enhances Alzheimer’s risk; choline reverses

Of course, this doesn't necessarily indicate that slamming down eggs and various flavors of choline supplements necessarily improves lipid balances in astrocytes in actual human brains functioning in the complicated federation of human and non-human cells that constitute our bodies. Well put. I do ...
by circular
Wed Mar 03, 2021 7:41 pm
Forum: Prevention and Treatment
Topic: BHRT talk with Bredesen, Hathaway and Julie G
Replies: 16
Views: 1026

Re: BHRT talk with Bredesen, Hathaway and Julie G

I use 100mg every other night because I have no interest in 2 straight weeks of poorer sleep. I recall reading a study that suggested continuous usage of progesterone worsened cognition, so I think there's something important about cycling it. That's an interesting approach! Do you seem to sleep as...
by circular
Mon Mar 01, 2021 8:38 pm
Forum: Science and Research
Topic: Covid vaccine safety for 4/4’s?
Replies: 32
Views: 3596

Re: Covid vaccine safety for 4/4’s?

Rainy wrote:...but I am so ready to hold those grandbabies, especially the two born while our family is carefully distancing during the pandemic! Patience!!

That must be downright agonizing. Hang in there!
by circular
Mon Mar 01, 2021 8:28 pm
Forum: Science and Research
Topic: Curcumin Article
Replies: 4
Views: 397

Re: Curcumin Article

Did you read the reviewers comments towards the end of the article. Decision letter https://doi.org/10.7554/eLife.63538.sa1 Author response https://doi.org/10.7554/eLife.63538.sa2 I have now ha! I've never seen that kind of thing published before. I'm none the wiser though. It's too complicated for...
by circular
Mon Mar 01, 2021 8:19 pm
Forum: Prevention and Treatment
Topic: BHRT talk with Bredesen, Hathaway and Julie G
Replies: 16
Views: 1026

Re: BHRT talk with Bredesen, Hathaway and Julie G

Did anyone else see this excellent panel discussion on Dr. Bredesen's Facebook page today? I'm glad to see the misconceptions on this topic addressed so intelligently. I've been on BHRT since around the age of 50 (now 56) though only recently found a practitioner who is taking a look at my hormone ...
by circular
Mon Mar 01, 2021 2:45 pm
Forum: Science and Research
Topic: Massive AD GWAS! YEAH!!!
Replies: 18
Views: 772

Re: Massive AD GWAS! YEAH!!!

WOW! Wish I had time to delve but need to get back to the day's to-do list.
Carlos Cruchaga at Washington University in St. Louis called the work a tour de force.
by circular
Mon Mar 01, 2021 2:39 pm
Forum: Science and Research
Topic: Curcumin Article
Replies: 4
Views: 397

Re: Curcumin Article

Another interesting article that has just been published, available free from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880682/pdf/elife-63538.pdf Curcumin promotes AApoAII amyloidosis and peroxisome proliferation in mice by activating the PPARa signaling pathway. Regards MoJoe Yikes! I'm rathe...
by circular
Mon Mar 01, 2021 2:31 pm
Forum: Prevention and Treatment
Topic: Toenail fungus - any implications for AD?
Replies: 7
Views: 475

Re: Toenail fungus - any implications for AD?

Hi, I've read that brain autopsies of elderly adults with Alzheimer's contained some types of fungi (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976758/). I'm wondering if toenail fungus (onychomycosis) can make it to the brain. I didn't find any indication it can in an internet search, so maybe ...

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