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by circular
Sun Sep 23, 2018 10:31 pm
Forum: Prevention and Treatment
Topic: What is considered atrophy in a brain structure per MRI volumetrics (NeuroQuant and Neuroreader)?
Replies: 27
Views: 1013

Re: What is considered atrophy in a brain structure per MRI volumetrics (NeuroQuant and Neuroreader)?

I wonder if you're aware there is a group of Shoemaker trained physicians who formed their own group, because while they recognize his contributions, they also came to believe that he wasn't scientific and flexible enough given new experiences as the patient load has expanded so much. Not to say who...
by circular
Sun Sep 23, 2018 9:22 pm
Forum: Prevention and Treatment
Topic: Dr. Gabriel Lyon - Benefits of High Protein
Replies: 29
Views: 2300

Re: Dr. Gabriel Lyon - Benefits of High Protein

So something new to think about here. I recently got Dr. Gundry's The Plant Paradox Cookbook . In the beginning he calls for moderation in meat and dairy because they contain Neu5Gc, 'which is associated with cancer and heart disease' [p. 24]. This concept may be in his Plant Paradox book as well bu...
by circular
Sun Sep 23, 2018 8:58 pm
Forum: Prevention and Treatment
Topic: What is considered atrophy in a brain structure per MRI volumetrics (NeuroQuant and Neuroreader)?
Replies: 27
Views: 1013

Re: What is considered atrophy in a brain structure per MRI volumetrics (NeuroQuant and Neuroreader)?

There is a Dr. GING that makes a powder that you can put along your gum line and it is helping with cavatations. It's called Oral Health. My doc told me about it. Another well known Lyme doc is using it in his patients too. Says we can avoid surgery with it. You can look him up on internet. He is a...
by circular
Sun Sep 23, 2018 7:22 pm
Forum: Prevention and Treatment
Topic: What is considered atrophy in a brain structure per MRI volumetrics (NeuroQuant and Neuroreader)?
Replies: 27
Views: 1013

Re: What is considered atrophy in a brain structure per MRI volumetrics (NeuroQuant and Neuroreader)?

Ive known Julie G for about 10 years. We were on a POTS forum together when I first got some of my DX. She helped many of us discover MCAS and get help for it. That's our Julie! I may know you too, but not from a POTS forum. I'm guessing you were on other forums covering EDS/MCAS/POTS and similar g...
by circular
Sun Sep 23, 2018 6:17 pm
Forum: Science and Research
Topic: Is ApoE4 Neanderthal?
Replies: 10
Views: 254

Re: Is ApoE4 Neanderthal?

I’m not sure, but I think they would already know whether Neanderthals had ApoE4. What I’ve read about is that certain of our HLA genes come from Neanderthals. I figure if Neanderthals were notably ApoE4 we’d already have heard it, but not sure. I think you must be right about that though?
by circular
Sun Sep 09, 2018 10:11 pm
Forum: Science and Research
Topic: Unusually strange dreams
Replies: 8
Views: 504

Re: Unusually strange dreams

A tip on using the site: You’ll have gotten a notification that I replied to your post. That is because I quoted you. If you are replying directly to an individual, as you graciously did to me, clicking on the quotation marks in upper right of post brings up the whole post. If it is a long one, you...
by circular
Thu Sep 06, 2018 12:11 pm
Forum: Prevention and Treatment
Topic: How could my homocysteine levels go up on B-complex
Replies: 16
Views: 794

Re: How could my homocysteine levels go up on B-complex

SusanJ wrote:
circular wrote:Does there happen to be a list anywhere of things that require SAMe to be metabolized?


Not that I'm aware. As far as I know, you pretty much have to look at individual metabolic pathways to see who needs methyl donors.

Thanks, I was curious in the context of SAM-e supplementation.
by circular
Wed Sep 05, 2018 9:18 am
Forum: Prevention and Treatment
Topic: How could my homocysteine levels go up on B-complex
Replies: 16
Views: 794

Re: How could my homocysteine levels go up on B-complex

SusanJ wrote:From a quick check, spironolactone needs SAMe to be metabolized.

Hi Susan! Does there happen to be a list anywhere of things that require SAMe to be metabolized?
by circular
Wed Sep 05, 2018 9:04 am
Forum: Prevention and Treatment
Topic: Advantages of genetic testing on Bredesen protocol treatment?
Replies: 11
Views: 649

Re: Advantages of genetic testing on Bredesen protocol treatment?

Are you able to elaborate on how your genetic information has been valuable for you? My choline-related genetics are all homozygously messed up on several SNPS. It took years for me to appreciate the extent of the issue and to adequately supplement to where I feel I've helped these broken pathways....
by circular
Wed Sep 05, 2018 8:56 am
Forum: Prevention and Treatment
Topic: Advantages of genetic testing on Bredesen protocol treatment?
Replies: 11
Views: 649

Re: Advantages of genetic testing on Bredesen protocol treatment?

You said you are certain you are an APOE4. If all of your affected family members have late-onset AD, then that's probably a good assumption. If some or all have early onset, though, there could be toxic exposure issues at work. Getting genotyped will let you verify or disprove your assumption abou...

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