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by apoe4thebetter
Fri Jan 22, 2021 7:56 pm
Forum: Science and Research
Topic: Urea's role in dementia
Replies: 11
Views: 3372

Re: Urea's role in dementia

Thanks for the quick reply, Tincup! It’s helpful to see in Dr. Rosedale’s summary a potential correlation between uric acid and cholesterol (had not seen that in the other materials I’m reading). That seems to resonate with my case—as I’ve done experiments to bring down cholesterol on a low-carb/hig...
by apoe4thebetter
Fri Jan 22, 2021 4:29 pm
Forum: Science and Research
Topic: Urea's role in dementia
Replies: 11
Views: 3372

Re: Urea's role in dementia

Just found this thread and wanted to ask if there is a preferred reference range for uric acid for E4s? I didn’t see anything about uric acid in either of Dr. Bredesen's books (might have missed it). I would understand if the confusing data about it caused it to be omitted for now as one of the “hol...
by apoe4thebetter
Wed Jan 20, 2021 10:31 am
Forum: Our Stories
Topic: 3/4 new here with high LDL after 3-months keto
Replies: 22
Views: 4503

Re: 3/4 new here with high LDL after 3-months keto

Thanks, Susan! Also appreciate your thoughts on non-dairy for coffee--I'm going to try the flax seed.
by apoe4thebetter
Tue Jan 19, 2021 12:49 pm
Forum: Our Stories
Topic: 3/4 new here with high LDL after 3-months keto
Replies: 22
Views: 4503

Re: 3/4 new here with high LDL after 3-months keto

It’s been another 3 months, and I’ve got a quick update with more lab cholesterol results from January 7 that are encouraging. I don’t have NMR results because of a centrifuge error, but I do have the traditional -C numbers and new-for-me ApoB. The bottom line is that after 3 months of switching to ...
by apoe4thebetter
Thu Nov 19, 2020 10:58 am
Forum: Our Stories
Topic: 3/4 new here with high LDL after 3-months keto
Replies: 22
Views: 4503

Re: 3/4 new here with high LDL after 3-months keto

Hi Anne, Thanks for sharing your story! We are not alone, and I also love coming here for inspiration. Sorry to hear about your mother. I would wonder if her blood glucose “in and out of diabetes range” would be a factor with her dementia given what I’ve read from Dr. Bredesen and others. The fastin...
by apoe4thebetter
Wed Nov 04, 2020 1:14 pm
Forum: Our Stories
Topic: 3/4 new here with high LDL after 3-months keto
Replies: 22
Views: 4503

Re: 3/4 new here with high LDL after 3-months keto

Here’s a quick update after my doctor’s appointment yesterday. Good discussion—she’s comfortable with where my lipids are, but A1c is creeping up again. That could be a side effect of the 2x500mg immediate-release niacin, and she’s aligned with the current thinking around high-dose IR niacin that no...
by apoe4thebetter
Fri Oct 23, 2020 3:54 pm
Forum: Our Stories
Topic: 3/4 new here with high LDL after 3-months keto
Replies: 22
Views: 4503

Re: 3/4 new here with high LDL after 3-months keto

Thanks, floramaria! I'm new to Berberine and wish I knew how much of the LDL-P improvement was influenced by it in my particular case (some don't notice any benefit). One challenge with it seems to be bioavailability because it can "self-aggregate" (ie. bond to itself) in the stomach and t...
by apoe4thebetter
Wed Oct 21, 2020 11:44 pm
Forum: Our Stories
Topic: 3/4 new here with high LDL after 3-months keto
Replies: 22
Views: 4503

Re: 3/4 new here with high LDL after 3-months keto

It been a while and wanted to provide an update on my n=1 experimentation since I have had some favorable results in terms of bringing down my LDL-P. I'm now following a diet that I’ve morphed into cyclic keto with some supplements and time-restricted eating. Let me first say that this experimentati...
by apoe4thebetter
Wed Jul 01, 2020 12:40 am
Forum: Our Stories
Topic: NMR Saturated Fat Experiment N=1
Replies: 5
Views: 2073

Re: NMR Saturated Fat Experiment N=1

I'm a 3/4. I've been testing my Lipids using NMR every 6 months since starting LCHF diet. After a year eating LCHF my numbers looked like this 6/7/19 LDL-P 1747 LDL-C 169 TC- 251 HDL-67 TG- 77 So I decided to try to replace saturated fats with MUFA, ( Olive oil, Avocado etc). Here are the results a...
by apoe4thebetter
Mon Jun 29, 2020 12:14 pm
Forum: Our Stories
Topic: 3/4 new here with high LDL after 3-months keto
Replies: 22
Views: 4503

Re: 3/4 new here with high LDL after 3-months keto

I did have a CRP test done last year, and it came back low, but I see there are lots of inflammatory markers. All of my "typical" inflammatory markers have been low, CRP, TNF-alpha, fasting insulin, except for A1c. But my TGF-beta test last summer was really high, so that's when we focuse...

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