Search found 123 matches: rapamycin

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by Julie G
Fri Sep 04, 2020 9:52 am
Forum: Prevention and Treatment
Topic: Sneak Preview of Dr. Bredesen's new Brain Food Pyramid
Replies: 17
Views: 1513

Re: Sneak Preview of Dr. Bredesen's new Brain Food Pyramid

... who finds the diet restrictive and has become glycotoxic again, and is (no surprise) backsliding. He's been exploring the idea of taking rapamycin vs. doing the actual work. I'll let you know if I hear any updates. In the meantime, Dr. Bredesen has published a similar series of case studies ...
by Newtothis3/4
Mon Aug 31, 2020 8:21 pm
Forum: Our Stories
Topic: Using RAPA for AD prevention
Replies: 39
Views: 7308

Re: Using RAPA for AD prevention

I decided not to take rapamycin ... mainly because I'd rather wait until an mTOR inhibitor is developed with a very short half-life, so that one could take it late in the evening and it would reinforce the natural mTOR rhythms of the ...
by circular
Wed Aug 19, 2020 9:57 am
Forum: Prevention and Treatment
Topic: Creating a successful case to my Dr for a CGM and Rapamycin
Replies: 2
Views: 324

Re: Creating a successful case to my Dr for a CGM and Rapamycin

... off track recently and I want to ask the Dr to give me a CGM to help me with compliance on my diet. I am also thinking about making a case to try Rapamycin instead of other immune suppressing drugs given the potential longevity benefits and the safety profile. Does anyone have experience of creating ...
by Tincup
Wed Aug 19, 2020 7:19 am
Forum: Prevention and Treatment
Topic: Creating a successful case to my Dr for a CGM and Rapamycin
Replies: 2
Views: 324

Re: Creating a successful case to my Dr for a CGM and Rapamycin

... off track recently and I want to ask the Dr to give me a CGM to help me with compliance on my diet. I am also thinking about making a case to try Rapamycin instead of other immune suppressing drugs given the potential longevity benefits and the safety profile. Does anyone have experience of creating ...
by vegarejuvinated
Tue Aug 18, 2020 10:57 pm
Forum: Prevention and Treatment
Topic: Creating a successful case to my Dr for a CGM and Rapamycin
Replies: 2
Views: 324

Creating a successful case to my Dr for a CGM and Rapamycin

... off track recently and I want to ask the Dr to give me a CGM to help me with compliance on my diet. I am also thinking about making a case to try Rapamycin instead of other immune suppressing drugs given the potential longevity benefits and the safety profile. Does anyone have experience of creating ...
by MichaelR
Mon Aug 03, 2020 10:32 am
Forum: Our Stories
Topic: Using RAPA for AD prevention
Replies: 39
Views: 7308

Re: Using RAPA for AD prevention

I decided not to take rapamycin ... mainly because I'd rather wait until an mTOR inhibitor is developed with a very short half-life, so that one could take it late in the evening and it would reinforce the natural mTOR rhythms of the ...
by circular
Sun Aug 02, 2020 2:38 pm
Forum: Our Stories
Topic: Using RAPA for AD prevention
Replies: 39
Views: 7308

Re: Using RAPA for AD prevention

I decided not to take rapamycin ... mainly because I'd rather wait until an mTOR inhibitor is developed with a very short half-life, so that one could take it late in the evening and it would reinforce the natural mTOR rhythms of the ...
by MichaelR
Sat Aug 01, 2020 4:13 pm
Forum: Our Stories
Topic: Using RAPA for AD prevention
Replies: 39
Views: 7308

Re: Using RAPA for AD prevention

I have read some newer articles with "low dose rapamycin," as low as 0.5 mg/kg in mice I'd like to see that 0.5 mg/kg study; please link or cite. In PMID 24341993 , 0.75 mg/kd per day of rapa had no effect on lifespan in male mice, and only ...
by lumia
Wed Jul 29, 2020 7:36 pm
Forum: Science and Research
Topic: Glucosamine: a mTOR inhibitor and autophagy activator?
Replies: 2
Views: 371

Glucosamine: a mTOR inhibitor and autophagy activator?

... formation of LC3 puncta, and increased LC3 turnover. This was associated with glucosamine-mediated inhibition of the Akt/FoxO3/mammalian target of rapamycin pathway. Administration of glucosamine to GFP-LC3-transgenic mice markedly activated autophagy in articular cartilage. Conclusion: Glucosamine ...
by LaderaJim
Mon Jul 20, 2020 2:24 pm
Forum: Science and Research
Topic: New Research on Blood Brain Barrier and APOE4
Replies: 10
Views: 1470

Re: New Research on Blood Brain Barrier and APOE4

Where can I find more inf on Rapamycin? How many people are are using it at what dosage level?

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