"The search for a blood test to diagnose Alzheimer's disease has been a long one, and researchers moved closer this year than ever before. In May, MedPage Today reported on an investigational blood assay for tau phosphorylated at threonine 181 (p-tau181). Here's a review of what's happened sinc...

From The Lancent, VOLUME 19, ISSUE 5, P422-433, MAY 01, 2020 Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts There's a link to the article below and a link to a medpagetoday article ...

I support a push.
Chris


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Thanks, Mike. I find the meetings very rewarding but I will be out of town. I hope one of the attendees can post a brief summary. Best, Chris The next meeting of the NORCAL meetup will be in a couple of weeks on Sunday February 16 at 10:00 am, in the same location as the last one - Peet's Coffee jus...

What wasn't clear to me in reading Peter Attia's analysis email or the paper was whether it was the people who had SNPs that lead to lower LDL-C or was it the people who had low LDL-C who were less likely to have cardiovascular disease. In the first case, it seems immaterial what my actual LDL-C is ...

Chris Masterjohn sent a series of emails on vitamins and minerals. His advice was to get natural sources of potassium in your diet and then salt (NaCl) to taste since your body has a natural ability to signal for salt based on its potassium level. He suggested that people consume 4,700-11,000 mg/d o...

Thank you for sharing, Brian. It's another good data point. From the study: ... all apoB particles are equally atherogenic. It sounds like they are saying apoB particles are necessary and sufficient. The other camp (Ivor Cummins, Dave Fledman, etc.) seems to agree on necessary but believe there need...

PBW wrote:I recently purchased" info red light therapy " light and have been using it for 15 minutes every night before sleeping.

Hi PBW - which brand did you settle on?
Chris

There was no association of alcohol use with dementia risk in APOE4 carriers…in fact the risk ratio was nearly flat across the 4 categories of alcohol intake. Curious. Hazard Ratios: # drinks/week none…..0.1-0.9…..1-7…..7.1-14…..14+ APOE E4 + 0.93……ref=1…….0.74…...0.77…...0.77 APOE E4 - 1.27……ref=1...

For those interested in the resveratrol I've been using, here's a link to it at amazon:
https://www.amazon.com/gp/product/B01E1 ... UTF8&psc=1
Chris