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by KatieS
Sun Jun 03, 2018 7:10 am
Forum: Our Stories
Topic: huge increase in Lp(a) - suggestions?
Replies: 6
Views: 1691

Re: huge increase in Lp(a) - suggestions?

LAC, I have a lp(a) at 75 mg/dl LabCorp and 207 nmol/L at Quest, repeatedly confirmed. Since I never had a lp(a) until age 63, I do not know the hormonal influence. Upon an increase of my estradiol patch to 0.025, my lp(a) did not significantly change. Do you have a high HDL? Mine is 118 which might...
by KatieS
Sat Jun 02, 2018 1:34 pm
Forum: Prevention and Treatment
Topic: Simvastatin and the ApoE4 Allele
Replies: 31
Views: 7297

Re: Simvastatin and the ApoE4 Allele

Hi Harrison - it does seem harder than it should be to see clear, consistent results in big studies, doesn't it? I spent some time recently re-reading those statin studies. It does seem that those big studies recalling past statin usage through middle age show positive effects while those assigning...
by KatieS
Thu May 31, 2018 12:29 pm
Forum: Prevention and Treatment
Topic: Simvastatin and the ApoE4 Allele
Replies: 31
Views: 7297

Re: Simvastatin and the ApoE4 Allele

The dose sounds too low to be therapeutic. I found that the muscle pain varied not just with the low dose, but also a different statin. ..Have you tried other statins? But it is therapeutic, or at least it reduces my LDL by 30%. Yes, I have tried many other statins. And yes, I have tried CoQ10. It ...
by KatieS
Thu May 31, 2018 7:55 am
Forum: Prevention and Treatment
Topic: Simvastatin and the ApoE4 Allele
Replies: 31
Views: 7297

Re: Simvastatin and the ApoE4 Allele

For me, I think the benefits outweigh the risks too. But, I just can't tolerate the muscle pain. I do get some benefit with micro doses. I take 5 mg Atorvastatin twice a week but need to take about every 4th week off as the muscle pain becomes intolerable enough that I am reluctant to exercise. But...
by KatieS
Mon May 28, 2018 11:52 am
Forum: Prevention and Treatment
Topic: Another negative lipid profile trend
Replies: 45
Views: 10577

Re: Another negative lipid profile trend

Jim, after trying three statins and two different doses, I finally settled on the same statin (SV) and the same dose (lowest 10mg) as my 3/4 mother has tolerated for decades. Should you have any close relatives who are on statins, ask them their experiences. Higher doses or potency statins halved my...
by KatieS
Sun May 27, 2018 3:08 pm
Forum: Prevention and Treatment
Topic: O.N.E. multivitamin Pure Encapsulations
Replies: 3
Views: 972

Re: O.N.E. multivitamin Pure Encapsulations

Like Susan, I've been taking O.N.E. for several years now. I like their vitamin B formulation,Co-Q, Zinc 25mg and eye vitamins. Of course, to lower my Hcy, I take space out taking more vitamin B during the day. Since I've been on a once a day vitamin for decades, I tend to avoid multivitamins that I...
by KatieS
Thu May 10, 2018 4:15 pm
Forum: Prevention and Treatment
Topic: HDL Too High?
Replies: 19
Views: 4413

Re: HDL Too High?

SGW, my HDL is now up to 118, but the particle count and size seems to point towards protective HDL. You might want to consider a lp(a) test as my test runs double normal, but there are preliminary mice studies that super-high HDLs might interfere with the lp(a) tests, skewing the test high. Do othe...
by KatieS
Thu May 10, 2018 4:07 pm
Forum: Prevention and Treatment
Topic: Vision Improvement!
Replies: 15
Views: 3149

Re: Vision Improvement!

Congrats ! I had a similar experience with my eyes dramatically improving, something I attributed to the drop in my homocysteine, antioxidant vitamins, etc... I no longer need glasses to drive.

Julie, are you concerned about the sunlight exposure increasing the cataract risks?
by KatieS
Fri Apr 06, 2018 10:19 am
Forum: Our Stories
Topic: Results from 1st bloodwork
Replies: 18
Views: 3695

Re: Results from 1st bloodwork

PBW, I didn't see your LDL-C which I was going to check if the LDL-P was concordant with a moderately high LDL-P. My LDL-C was only 110, but my LDL-P was 1784, reflecting another risk factor of discordance. Judging on you high total cholesterol, despite our both having very high HDLs, I suspect you ...
by KatieS
Wed Mar 28, 2018 8:35 pm
Forum: Our Stories
Topic: Another personal loss to AD
Replies: 18
Views: 3343

Re: Another personal loss to AD

Brian, your mother is likely to feel so grateful to have you during this grieving process starting with her sister's decline. You described it so aptly as "paralyzing" to recognize a loved one's lapses.

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