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by aphorist
Mon Mar 30, 2020 1:35 pm
Forum: Science and Research
Topic: Online Alzheimer's Afternoons Seminar Series
Replies: 13
Views: 2256

Re: Online Alzheimer's Afternoons Seminar Series

Fiver wrote:I took notes and plan to post summaries here, if that helps.


If you can post yesterday's summar, I'd be interested. I just saw this link you provided and yesterday's topic looks interesting. Today, not so much.
by aphorist
Sat Mar 28, 2020 1:46 am
Forum: The Social Hour
Topic: COVID-19 Recommendations from U of AZ
Replies: 15
Views: 3048

Re: COVID-19 Recommendations from U of AZ

Selenium is an important nutrient. It's important to not be deficient in any vitamin or mineral going into a virus. But what Dr. Crouse appears to do is take his background and underlying concerns in ROS/metal ions and then shoehorn it into a solution for a viral lung infection. His logic reads to m...
by aphorist
Sun Mar 22, 2020 5:49 pm
Forum: Science and Research
Topic: APOE4 people smarter?
Replies: 6
Views: 1348

Re: APOE4 people smarter?

Overall, full-scale IQ scores were lower by 1.91 points for each APOE4 allele an individual carried. A person can have up to two APOE4 alleles, and the gene's effect on IQ performance multiplies with each allele present. Boys scored .33 points lower on IQ tests, and girls scored almost 3 points low...
by aphorist
Fri Mar 13, 2020 1:48 pm
Forum: Science and Research
Topic: Does having APOE4 protect you from getting the Coronavirus? .... Maybe
Replies: 27
Views: 5437

Re: Does having APOE4 protect you from getting the Coronavirus? .... Maybe

First clinical trial for Coronavirus - 24 G IV infusion of Vitamin C https://clinicaltrials.gov/ct2/show/NCT04264533 It's a very high amount, probably to prove efficacy. Normal IV's are like 10-15 grams. But, long story short if you have some vitamin C daily... even like 200 mg, it will likely help...
by aphorist
Sat Feb 29, 2020 9:16 am
Forum: Science and Research
Topic: Does having APOE4 protect you from getting the Coronavirus? .... Maybe
Replies: 27
Views: 5437

Re: Does having APOE4 protect you from getting the Coronavirus? .... Maybe

First clinical trial for Coronavirus - 24 G IV infusion of Vitamin C https://clinicaltrials.gov/ct2/show/NCT04264533 It's a very high amount, probably to prove efficacy. Normal IV's are like 10-15 grams. But, long story short if you have some vitamin C daily... even like 200 mg, it will likely help ...
by aphorist
Mon Feb 10, 2020 7:22 pm
Forum: Science and Research
Topic: Video APOE, APOE4, Cholesterol, LDL & Insulin Resistance
Replies: 6
Views: 1408

Re: Video APOE, APOE4, Cholesterol, LDL & Insulin Resistance

Decent overview. Horrible intro music. He needs to be checked for dementia for inserting that for 3 minutes in the beginning.
by aphorist
Tue Jan 28, 2020 9:07 am
Forum: Science and Research
Topic: Idazoxan - University of Alabama research
Replies: 2
Views: 710

Re: Idazoxan - University of Alabama research

In my estimation, this paper is huge. It mechanistically shows how Abeta initiates the cascade to phospho-tau. Shows how idazoxan and lithium inhibit phospho-tau and rescue alzheimer's. This paper is just enormously important. https://www.alzforum.org/news/research-news/shot-adrenaline-amyloid-v-sp...
by aphorist
Mon Jan 27, 2020 6:15 am
Forum: Science and Research
Topic: B12 and APOE4 - a gene-micronutrient interaction
Replies: 12
Views: 2597

Re: B12 and APOE4 - a gene-micronutrient interaction

I can't figure out the conversion on those figures. The data I have is in nmol/L.
by aphorist
Sun Jan 26, 2020 6:54 pm
Forum: Science and Research
Topic: B12 and APOE4 - a gene-micronutrient interaction
Replies: 12
Views: 2597

Re: B12 and APOE4 - a gene-micronutrient interaction

Thanks, Aphorist, my B12 plasma levels are never that low (always 1500 or above), even when I stop supplementing for a few days before a test. (Perhaps I need to stop supplementing for a whole week before a blood draw?) Recently, I was asked to increase my daily dose due to my MMA levels indicating...
by aphorist
Wed Jan 22, 2020 7:13 pm
Forum: Science and Research
Topic: B12 and APOE4 - a gene-micronutrient interaction
Replies: 12
Views: 2597

Re: B12 and APOE4 - a gene-micronutrient interaction

I think there is some mistake about comparing these two studies. The first study is a median follow-up period of 8.2 years, in which they evaluate mortality and find it to be increased in the upper quartile of B12. The second study BrianR mentions is a very short term ICU (Intensive Care Unit) analy...

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