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by Fiver
Mon Mar 30, 2020 8:47 am
Forum: Science and Research
Topic: Online Alzheimer's Afternoons Seminar Series
Replies: 13
Views: 1156

Online Alzheimer's Afternoons Seminar Series

For those interested in the nuts and bolts details of AD research I wanted to let you know of a Alzheimer's Afternoons Seminar Series that is occurring online during the COVID-19 shut down. It is focused on apoe. It is run by a group of researchers as a lab seminar series, organized via Twitter by A...
by Fiver
Mon Mar 30, 2020 8:33 am
Forum: Our Stories
Topic: Update
Replies: 14
Views: 1087

Re: Update

Thanks NF52 :)
by Fiver
Mon Mar 30, 2020 7:44 am
Forum: Our Stories
Topic: Update
Replies: 14
Views: 1087

Update

My mom passed quietly yesterday. She was 76. It was an odd situation, with her care facility in lock down. No one had seen her in weeks, except by phone. It was just the end stage of the disease, nothing unexpected at this point. But she got good care and was able to be transferred out in time that ...
by Fiver
Mon Mar 30, 2020 7:00 am
Forum: Prevention and Treatment
Topic: How to change size of lipid particles
Replies: 13
Views: 1826

Re: How to change size of lipid particles

Hi Eric. Yes, I was on atorvastatin 20 or 40mg for 3-4 years. Before that my cardiologist had me on the high dose, slow release niacin - which has fallen out of favor now. I started to have the muscle issues that are sometimes associated with statins. 40 mg really was tough. After I got a clean calc...
by Fiver
Mon Mar 16, 2020 1:50 pm
Forum: Science and Research
Topic: Risks and benefits of apoe2 vs apoe4 in a 5,000-person neuropathological study
Replies: 2
Views: 511

Re: Risks and benefits of apoe2 vs apoe4 in a 5,000-person neuropathological study

Hi NF52. Thank you! I've been away from the site for a few days as I shut down my lab and started to transition to teaching online. My mom's memory care facility was locked down a few days ago - she is fine but of course I worry abut how all this will play out in the coming weeks. You are absolutely...
by Fiver
Thu Mar 12, 2020 6:59 pm
Forum: Prevention and Treatment
Topic: How to change size of lipid particles
Replies: 13
Views: 1826

Re: How to change size of lipid particles

What I know, there are *correlated* with greater HDL: niacin, statins, higher estrogen/lower testosterone patterns in females vs. males (up until menopause). This is from memory, I haven't red about this in a year or so.
by Fiver
Thu Mar 12, 2020 6:48 pm
Forum: Science and Research
Topic: Risks and benefits of apoe2 vs apoe4 in a 5,000-person neuropathological study
Replies: 2
Views: 511

Risks and benefits of apoe2 vs apoe4 in a 5,000-person neuropathological study

Hello everyone, I don't know if this has been posted before. I didn't see it when I checked. This table: https://www.nature.com/articles/s41467-019-14279-8/tables/2 From this recent study: https://www.nature.com/articles/s41467-019-14279-8 Really brought me down. I guess it's been a while since I re...
by Fiver
Fri Feb 28, 2020 10:34 am
Forum: Prevention and Treatment
Topic: Blue Cross Plans Say Alzheimer’s Has Tripled Among Adults Ages 30 To 64
Replies: 5
Views: 867

Re: Blue Cross Plans Say Alzheimer’s Has Tripled Among Adults Ages 30 To 64

Hi. Thanks for sharing. The disconnect between the scale of the problem and the resistance to doing much of anything to reduce risk at the level of populations is disappointing. In our area we have horrible air pollution, mostly PM2, one of the older populations of any state, and high and increasing...
by Fiver
Tue Feb 11, 2020 6:50 am
Forum: Science and Research
Topic: 2019 review on APOE4 and AD
Replies: 1
Views: 292

Re: 2019 review on APOE4 and AD

I read this. Thanks for sharing! It's a good overview of the current apoe4 research. It might be worth linking somewhere for new folks. I wish they were further along on these approaches to addressing apoe4 directly.
by Fiver
Mon Feb 03, 2020 1:02 pm
Forum: Science and Research
Topic: Plant flavonols significantly reduce Alzheimer’s risk
Replies: 8
Views: 676

Re: Plant flavonols significantly reduce Alzheimer’s risk

I love plant polyphenols and I'm not surprised that they reduce risk. They found reduced risk associated with kaempferol, myricetin, and isorhamnetin. They state they found not risk reduction associated with quercetin but their data kind of suggests that a larger study might detect that as well. I'm...

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