Hi. Good questions! Maybe this could help: The mitochondria are indeed passed down from moms, except in very rare and extraordinary circumstances. But their circular chromosome is relatively small. Over the course of evolution many of the mitochondrial genes have been transferred from the mitochondr...

Talked with Denesey, who seems very nice. While they might be flexible on the age requirement they are focusing only on individuals with some diagnosed MCI. Makes sense. They want to be able to show improvement, if it occurs. But they are still looking for participants.

Sulforaphane crosses the BBB and acts as an indirect anti-oxidant. It activates other natural anti-oxidant systems, lasting days compared to just hours for traditional anti-oxidants like vitamin C. So, that's another one.

Yes. The evidence is strong and accumulating. Not just for AD but also other dementias and Parkinson's disease, not to mention the rock solid evidence it contributes to CVD. Unfortunately, the nation isn't doing much about it. In fact, PM2.5 pollution is up in recent years, after declining for almos...

Thanks for sharing. I can see how this would be a huge help for research. And maybe we could know if our interventions are working. That would be good. But I have to admit my first thought was: this is terrifying. How would things change - insurance, job clearances, etc. - to have this on a medical ...

Wow! What a great resource. Thanks for taking this on!

It's so nice to see the Hazard Ratios going in the "good" direction. Thanks for sharing. Off to the gym.

That's one heck of a class.

Read this too. While I love that this is a natural product from a seaweed, I am not getting my hopes up too high. The strategy is to use the seaweed compound to modify the gut flora to prevent leaky gut and inflammation of the brain. Seems early in the discovery process, and China is speeding up the...

Saw this too. This seems like a really important clue!