Are you able to elaborate on how your genetic information has been valuable for you? IMO, APOE4 status is only one piece of information that can help you take action to increase your healthspan. Knowing my MTHFR and other methylation-related genes status helped me realize I'm an undermethylator, an...

I have read Dr Bredesen’s book & done some research but I was hoping someone might be able to clearly explain to me what the advantages of getting genetic testing done is in terms of treatment? Or where I could find a clear outline of what you do differently based on each genetic status? There ...

I too have had difficulties with not getting enough deep sleep, and it [Oura ring] has helped me to determine whether various interventions are working. I have had some success with increasing my deep sleep. I have just started tracking sleep, and the initial data shows I am not getting enough deep...

Unfortunately, I don’t know the answers to your questions about coffee, but I wanted to comment on managing low COMT activity. Chris Masterjohn has a podcast episode on managing COMT status by addressing methylation. He has a second podcast about living with MTHFR that provides a protocol for enhanc...

Because of my "dry eye" I now sleep with a humidifier. Might that help you? Of course everything depends upon your individual needs. I also use a white noise machine. I have a trick to shut down my thinker so that I can go to sleep: I play classical music in my head, no words. I have a dr...

One more gadget to add to the list: I just ordered a Whoop strap, which is a device you wear on your wrist that tracks HRV with four other variables on a 24/7 basis. It's popular among elite athletes (a group of which I am NOT a member :) ), and the platform analyzes the data to help you maximize re...

I like a lot of the ingredients and doses. I couldn't take it because it has copper, a significant amount of Vitamin E, and calcium. If your copper/zinc ratio is good (1:1), copper may not be a problem. You can find out if you have the risk allele for Vitamin E supplementation by running raw genetic...

Thanks for the link! I just finished listening to Rhonda's Found My Fitness interview with Valter Longo. I did an 18-hour fast yesterday as a result, and I'm picking up a copy of his book, the Longevity Diet. The list of topics Rhonda covers in the Scott Eastwood interview looks like it will answer ...

These bands wrap around the upper arm (near the shoulder) or upper leg/thigh. There's lots of products out there and I think they are mostly based off the Kaatsu compression sleeves which are much fancier/expensive. I picked up a pair of the BFR brand bands. The idea is you can do a lighter version...

In episode 43 of Chris Masterjohn's podcast, he says that niacin and nicotinamide riboside tax the methylation system. (It's at 48:20 in the recording.) I have been taking the Thorne Niacel product that contains 250 mg of Niagen per capsule, but I'm planning to cut that to 100 mg per day to avoid m...