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by RichardS
Mon Dec 29, 2014 2:57 pm
Forum: ApoE4.Info, Inc.
Topic: WIKI wonders
Replies: 30
Views: 7984

Re: WIKI wonders

I am also quite familiar with Davis' stance on apoe4 carriers. The problem I had when I followed up with him about this is that I also have elevated Lp(a). A primary proven intervention to decrease it (and it is still up for debate if that will actually improve one's cardiovascular status) is to inc...
by RichardS
Sun Dec 28, 2014 2:58 pm
Forum: Prevention and Treatment
Topic: SFA: Apparently, context matters
Replies: 83
Views: 20636

Re: SFA: Apparently, context matters

...After you've all actually read Part VI then tell me particle size somehow matters more than particle count in assesing the optimal health program. Its just not congurent with the facts. Has anyone actually read it? I don't need to prove whats already been proven and explained. http://eatingacade...
by RichardS
Thu Dec 25, 2014 11:15 am
Forum: Prevention and Treatment
Topic: SFA v Carbs v MUFA's: clinical trial divided by apoe type
Replies: 16
Views: 4588

Re: SFA v Carbs v MUFA's: clinical trial divided by apoe type

Russ, What strikes me about the data in that PDF is that: (1) MUFA heavy diets result in 0.4-0.5 mmol/L lower LDL-C for all 3 groups. How this interacts with the fact that 3/4's start with a higher baseline is up for debate. (2) The main variation is that 3/4's show a (significantly?) lower MUFA-ind...
by RichardS
Mon Dec 22, 2014 4:35 pm
Forum: Prevention and Treatment
Topic: Lets talk about eggs
Replies: 30
Views: 8772

Re: Lets talk about eggs

Thanks again Richard. I saw that superscript "a" note too but they didn't clarify whether the response was good up or down and for which variable. In the Lehtimaki study one wonders what else and in what quantities the 4/4s were eating with the same constituents as the egg yolks. Since E4...
by RichardS
Mon Dec 22, 2014 8:51 am
Forum: Prevention and Treatment
Topic: Lets talk about eggs
Replies: 30
Views: 8772

Re: Lets talk about eggs

Thanks Richard. I'm having trouble interpreting the chart. It seems they don't say whether the effect is favorable or unfavorable for which variable in the far right columns? I can guess, but am I missing something? Understandable. Hidden at the bottom of the table is the footnote that says entries...
by RichardS
Sun Dec 21, 2014 12:31 pm
Forum: Prevention and Treatment
Topic: Lets talk about eggs
Replies: 30
Views: 8772

Re: Lets talk about eggs

Another very well controlled study with subjects grouped by 3/2, 3/3, 3/4 status includes a very informative table reviewing human apoe diet studies. I highlighted the 5 that manipulated dietary cholesterol while trying to hold macronutrient ratios constant: Tso et al 1998 Table 8 - diet induced lip...
by RichardS
Sun Dec 21, 2014 11:32 am
Forum: Prevention and Treatment
Topic: Dietary Ketosis Aids Memory in Mild Cognitive Impairment
Replies: 63
Views: 14256

Re: Dietary Ketosis Aids Memory in Mild Cognitive Impairment

The one thing I would plead for people to report on is weight and/or caloric intake change . When I see someone say they starting eating more eggs or ghee or coconut oil or whatever and a few weeks later had improved biomarkers, I need to hit the virtual delete key because we know many people respo...
by RichardS
Sun Dec 21, 2014 11:13 am
Forum: Prevention and Treatment
Topic: Lets talk about eggs
Replies: 30
Views: 8772

Re: Lets talk about eggs

One of the classic studies quoted in the first video is this one: Full text: http://www.jci.org/articles/view/117705 Effects of dietary cholesterol and fat saturation on plasma lipoproteins in an ethnically diverse population of healthy young men. It appears to be a very well controlled study that h...
by RichardS
Sat Dec 20, 2014 10:22 am
Forum: Prevention and Treatment
Topic: Lets talk about eggs
Replies: 30
Views: 8772

Re: Lets talk about eggs

Hep, Thank you so much for starting this thread. It is definitely worthy of a deep look. You posted a lot of links, so it will take me a while to dig through it, but based just on the snippets you posted in your message, it seems you are only quoting epidemiological studies. There are human clinical...
by RichardS
Sat Dec 20, 2014 10:10 am
Forum: Prevention and Treatment
Topic: Dietary Ketosis Aids Memory in Mild Cognitive Impairment
Replies: 63
Views: 14256

Re: Dietary Ketosis Aids Memory in Mild Cognitive Impairment

Regarding the skepticism issue, I would like to point out that any dietary 6-week intervention with people who have cognitive impairment that shows a positive effect is impressive to me. GB, I know we E4's really want to find outcome based studies that break down the subject groups by apoe status. W...

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