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by RichardS
Tue Dec 22, 2015 1:00 pm
Forum: Announcements and Events
Topic: 2016 Meet-Up
Replies: 125
Views: 29621

Re: 2016 Meet-Up

Quick update on the tentatively proposed meet-up in April; it’s fallen through. The LA symposium is apparently limited in space and primarily open to AD researchers. I've emailed the conference coordinator to get further information. They may let me in given my neuroscience background and universit...
by RichardS
Wed Dec 09, 2015 3:31 pm
Forum: Science and Research
Topic: Peer Review Cautions
Replies: 10
Views: 2599

Re: Peer Review Cautions

...it is now easy to do a small forray into looking at snp correlation with whatever strikes the researcher's fancy. I predict we will see thousands of these and most likely most will be dead ends for us. That's why I intend not to go exome diving. I'm not even 23andme data diving. Seen this first ...
by RichardS
Thu Dec 03, 2015 5:48 pm
Forum: Announcements and Events
Topic: 2016 Meet-Up
Replies: 125
Views: 29621

Re: 2016 Meet-Up

I'm up for the L.A. meeting in April.
by RichardS
Wed Nov 04, 2015 7:15 pm
Forum: Prevention and Treatment
Topic: Low Fat vs. Low Carb
Replies: 94
Views: 19051

Re: Low Fat vs. Low Carb

got it Effects of apolipoprotein E genotype on dietary-induced changes in high-density lipoprotein cholesterol in obese postmenopausal women. (Nicklas et al 2002).pdf Moderator note - I deleted the attached paper (PMID: 12077730) because our copyright infringement policy prohibits it. Members in jur...
by RichardS
Tue Oct 27, 2015 5:24 pm
Forum: Prevention and Treatment
Topic: Paper Access Help: Assoc of ApoC3 Loss-of-Function Mutations w/ Plasma Lipids & Subclinical Athero.
Replies: 3
Views: 1326

Re: Paper Access Help: Assoc of ApoC3 Loss-of-Function Mutations w/ Plasma Lipids & Subclinical Athero.

It looks like that issue is not yet in PubMed, so I can't use my usual access point. Sorry. If nobody else can get it now, bump up this topic in a few weeks or PM me.
by RichardS
Thu Oct 15, 2015 1:53 pm
Forum: Science and Research
Topic: EEG Tech to help AD patients
Replies: 5
Views: 1430

Re: EEG Tech to help AD patients

Having had some clinical and research experience with EEG and neurofeedback and attending a couple conferences where these devices are promoted, I would say don't get too excited. There are definitely great gains being made with EEG directed human-machine interfaces, but I have not seen anything abo...
by RichardS
Thu Oct 15, 2015 1:45 pm
Forum: Prevention and Treatment
Topic: New Alzheimer's treatments may arise from modeling 'heat shock proteins'
Replies: 4
Views: 1315

Re: New Alzheimer's treatments may arise from modeling 'heat shock proteins'

Richard, do you think if we exercise well over the 60% max (i.e. 80% for 40 minutes), produce the HSP benefits earlier than "180 minutes of exercise"? Am I correctly reading 3 hours of exercise at 60%max? I'm viewing this as a proof of concept piece rather than a source of guidance about ...
by RichardS
Tue Oct 13, 2015 5:57 pm
Forum: Prevention and Treatment
Topic: New Alzheimer's treatments may arise from modeling 'heat shock proteins'
Replies: 4
Views: 1315

Re: New Alzheimer's treatments may arise from modeling 'heat shock proteins'

It looks like exercise can also affect heat shock proteins in human brains in vivo: Full text: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065286/ Exercise induces the release of heat shock protein 72 from the human brain in vivo G. I. Lancaster,1 K. Møller,2 B. Nielsen,3 N. H. Secher,4 M. A. Febbr...
by RichardS
Mon Oct 05, 2015 5:23 pm
Forum: Prevention and Treatment
Topic: Cognition improved with neutraceuticals
Replies: 10
Views: 2631

Re: Cognition improved with neutraceuticals

Sorry, can't get a free copy. Here is the original abstract from the paper: Thirty-four individuals with mild cognitive impairment were randomized for 6 months to a nutraceutical formulation (NF: folate, alpha-tocopherol, B12, S-adenosyl methioinine, N-acetyl cysteine, acetyl-L-carnitine) or indisti...
by RichardS
Thu Sep 24, 2015 3:50 pm
Forum: Prevention and Treatment
Topic: Vitamin D: Don't Overdo a Good Thing
Replies: 42
Views: 10095

Re: Vitamin D: Don't Overdo a Good Thing

For a long time I have had this persisting concern that all sorts of chronic conditions for which vitamin D has been flagged as low and a risk factor suffer from a spurious correlation. I have strong suspicions that many of those conditions likely find sufferers more bound to the indoors where perso...

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