No, he's not, unfortunately, but I was hoping that the drug would have been approved in the next year or so. I have been following your posts and was very optimistic. It is so disappointing!!!

Hi NF52: This is all well for people that are healthy but some people are desperate to try something that might work. I do know that science works slowly but boy, I cannot help but feel very angry at this turn of events. I have a brother that has MCI for the last 2 years and he's been kept stable wi...

I'm ready to just go without supplements , but I did before I switched to a ketoflex and it jumped to 12.1 Your body gets rid of excess niacin by using up methyl groups. So those B vitamins you are taking are diverted to getting rid of excess niacin from the 500 mg you are taking, and are not being...

Thank you Susan: Originally, I wasn't taking Niacin. I was doing a zero carb diet and my cholesterol went thru the roof, that's why she recommended Niacin. Now, I don't know if the Niacin did the trick with the cholesterol or it was the change in diet. I'm going to message her and maybe she can give...

Any ideas? You might experiment with adding choline (or phosphatidylcholine) and/or creatine. See Chris Masterjohn's take on treating MTHFR. I used both PC and creatine on top of things in your list (but smaller amounts of methyl-folate at 400 mcg/day) to drop mine from 10.4 to 6.9. I tried the PC ...

Hi J11: Thank you J11 for all your hard work in trying to make this topic easier to understand.

I do hope that they approve it, although from what I'm reading in the news, it's going to be difficult.

Just wanted to mention that even if we don't comment, we are noticing and reading.

Roxanne

Hi Roxanne, I just take 1 capsule of the Swanson B-complex but also take an extra 12.5mg lozenge of P5P and 500mg TMG. Because both my B12 and Folate levels were crazy high and my homocysteine was not reducing, I halved both of these and followed Chris Masterjohns protocol with sunflower lecithin (...

Thankyou Susan and Floramaria. Yes I will stick with Iherb for the bulk of my supplements. I did order a multiB Complex (recommended by Rhonda Patrick for some family members) from Swanson some weeks ago and I’m sure it’s on its way somewhere. With all the lockdowns worldwide the delay is to be exp...

Thank you for your notes Fiver. It probably takes a big chunk of your time. I'm with SusanJ. As a 3/4, I don't see as much success in a Keto Diet as others with 4/4 seem to have. And I struggle and tweak and go on. In any case, these perspectives are very interesting and hopefully something soon wil...

So Sorry for your loss FitFoodie, SusanJ and NF52. Let's hope that all this suffering soon comes to an end. SusanJ, it's comforting to know that your SIL's mother is well now. Sending positive energy your way.