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by Lucy5
Mon Oct 05, 2015 1:33 pm
Forum: Science and Research
Topic: Methylation differences in APOE4s
Replies: 5
Views: 1248

Re: Methylation differences in APOE4s

My thinking here based on my understanding (limited as it is at this point) of the complexities of the AD process, is that for those of us who do have methylation issues specifically due to mutations of MTHFR (w/emphasis on 2 copies which severely limit the ability to use folate) is that we can't af...
by Lucy5
Mon Oct 05, 2015 11:52 am
Forum: Prevention and Treatment
Topic: Cognition improved with neutraceuticals
Replies: 10
Views: 2131

Re: Cognition improved with neutraceuticals

Also whether the MTHFR gene was controlled for. I'd also like to know what folate formulation was used. My thinking here being that if the study included those with the MTHFR mutation (esp 2 copies), then adding the methylated forms of folate & B12 might contribute to the improvements seen? Just...
by Lucy5
Sun Oct 04, 2015 11:39 pm
Forum: Science and Research
Topic: Gladstone salsalate drug study
Replies: 7
Views: 2259

Gladstone salsalate drug study

I am new to this site and so excited to have found it! Since learning my ApoE status a couple of years ago (during a routine blood test), I have felt very much alone and have been doing my own research. I've been following Dr. Mahley and the Gladstone for some time and feel hopeful about their resea...

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