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by frankiesfriend
Sun Nov 03, 2019 7:02 am
Forum: Prevention and Treatment
Topic: Sleep Tracker
Replies: 31
Views: 10159

Re: Sleep Tracker

I bought an Oura ring about a month before the polysomnography (PSG) study I underwent about three months ago. The PSG indicated I had mild sleep apnea during REM sleep, and ZERO deep sleep. My sleep doctor recommended a CPAP but did not seem to care about the deep sleep. When I pressed for more inf...
by frankiesfriend
Sat Oct 26, 2019 3:44 pm
Forum: Prevention and Treatment
Topic: Lithium for AD prevention?
Replies: 4
Views: 1505

Lithium for AD prevention?

A new review paper in the Journal of Neurodegenerative Diseases recounts the familiar lifestyle recommendations of healthy diet, lower stress, exercise and sleep for lowering the risk of developing Alzheimer's, as well as treating early symptoms. Additionally, the authors cite lithium deficiency as ...
by frankiesfriend
Mon Oct 21, 2019 1:59 pm
Forum: Science and Research
Topic: New study - alcohol and dementia risk
Replies: 3
Views: 1324

New study - alcohol and dementia risk

Alcohol Consumption and Risk of Dementia and Cognitive Decline Among Older Adults With or Without Mild Cognitive Impairment JAMA Network Open, September 27, 2019 - Koch, Manja, et al. (Article is open to the public, but I could not get a hyperlink to work.) This study extracted data from the Gingko ...
by frankiesfriend
Sat Oct 19, 2019 6:30 am
Forum: Getting Started
Topic: Intermittent Fasting
Replies: 72
Views: 23456

Re: Intermittent Fasting

I have been doing 16:8 IF for several years, but I have been thinking for a long time that I should embark on longer fasts, as is recommended by many in this forum who have benefited as well as many in the functional medicine health podcast arena. My overall goal would be as a tune up of general hea...
by frankiesfriend
Sat Oct 05, 2019 11:56 am
Forum: Science and Research
Topic: Lifestyle changes may not help Apoe4s
Replies: 14
Views: 3787

Re: Lifestyle changes may not help Apoe4s

After spinal fusion surgery on my lower back six years ago, I developed neuropathic symptoms (deep, aching pain and parathesias in my legs and feet), which greatly impacted my stamina and mobility. My neurologist prescribed gabapentin for neuropathy, but offered no other treatment. I sought a second...
by frankiesfriend
Fri Jul 19, 2019 3:53 pm
Forum: Science and Research
Topic: New article on exercise released this week
Replies: 2
Views: 929

Re: New article on exercise released this week

This impressive research hints at the mechanisms by which physical activity protects the aging brain. "Hippocampal gene expression patterns linked to late-life physical activity oppose age and AD-related transcriptional decline" Nicole C. Berchtold a,*, G. Aleph Prieto a, Michael Phelan b,...
by frankiesfriend
Tue Jul 02, 2019 5:35 pm
Forum: Science and Research
Topic: Sleep as a potential biomarker of tau and β-amyloid burden in the human brain
Replies: 6
Views: 2146

Re: Sleep as a potential biomarker of tau and β-amyloid burden in the human brain

In a typical polysomnography used to evaluate sleep apnea or other sleep disorders, do they look at spindle coupling and amplitude which is indicated in this paper to correlate to tau and amyloid accumulation? I am interested in obtaining a sleep study due to a recent history (five years) of poor sl...
by frankiesfriend
Mon Jul 01, 2019 7:10 am
Forum: Science and Research
Topic: More info on why APOe4 may be worse for women-And what you can do about it.
Replies: 2
Views: 1157

Re: More info on why APOe4 may be worse for women-And what you can do about it.

Is there any evidence that tau accumulation is reversed by lifestyle changes embodied in RECODE, or are the improvments observed in early AD by following the Bredesen protocol compensatory to a fixed pathology?
by frankiesfriend
Tue Jun 25, 2019 5:27 pm
Forum: Our Stories
Topic: New this year - intro and question
Replies: 1
Views: 794

New this year - intro and question

Last winter I was happy to find this web group and discover the wealth of information offered herein. Like many others, I have concerns about my risk of developing AD, having watched my mother’s struggles with her ever increasing confusion, anxiety and loss of autonomy leading up to her death at age...
by frankiesfriend
Sun Mar 10, 2019 10:08 am
Forum: Our Stories
Topic: DISAPPOINTING RESULTS
Replies: 20
Views: 6029

Re: DISAPPOINTING RESULTS

Hi Roxanne, The low weight, high energy, sleeplessness, anxiety and increased blood pressure, as well as increased cholesterol, were all symptoms I experienced one year when I was hyperthyroid (too much thyroid hormone) - probably induced by stress. If you were taking T3, then you probably were unde...

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