I have only seen studies that link high saturated fat intake in E4 carriers to high LDL. They all beg the question of the lipid hypothesis' validity and conclude that saturated fat is bad for E4 carriers. I would be thrilled to see even one study linking saturated fat intake or LDL to all cause mort...

Here's a new review that looks at 68,000+ people aged 60+: Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review One of the 19 cohort studies was the Scandinavian one discussed above. This is a substantial body ...

I have not read anything indicating that Dr. Gundry sees adiponectin as a therapeutic target. I think he just sees it as an indicator that lectin avoidance may be a useful tool to reduce systemic inflammation. The actual therapeutic target biomarker is TNF-alpha. I do think adiponectin is an interes...

Nancy, I also recommend these two recent threads to you. They showcase a range of opinions and evidence and may help you refine your own point of view. Because you are going to hear lots of conflicting advice here and everywhere else in your life, I think learning enough to make your own choices con...

Oh, wow, I didn't know that about the calcium! If your primary care doctor recommends calcium to you - my wife's doctor did so within the past year - you may want a deeper understanding of the issues to help you decide what to do. Dr. Jason Fung, an uncommonly sharp young nephrologist from Toronto,...

GeorgeN, that helps clear up the high or low carb diet mixed messages we get from the different cardiologist's diets a little. It helps explain why I may not be losing weight on Esselstyn's diet. By adding nuts and olive oil, fish oil, I guess that messes it up. Nancy, I think it's fascinating that...

I'm right there with you, ApropoE4. This conversation reminds me of this article - https://www.quantamagazine.org/20160421 ... t-reality/ - as well as the recent revelation that Elon Musk thinks we may be characters in a computer simulation.

+1

Many of us are aware that normal variations in red blood cell turnover can account for large variations in HbA1c test results from one person to another and introduce substantial uncertainty regarding estimated average blood glucose levels. Starting at 11:00 in this fascinating podcast from Dr. Chri...

I tested in current versions of Chrome, IE 11, and Firefox, and once I log into any Google account in any tab of one of those browsers, I'm no longer anonymous in Sheets. This does seem likely to trip up people who are trying to maintain anonymity. The behavior doesn't persist in the incognito (Chro...