What complicates this is that it is generally considered that the brain makes all its own apoE and the the plasma apoE all comes from the liver, and the two pools do not mix. But maybe that breaks down in Alzheimer's disease with the leaky blood brain barrier? Harrison -- Very good point. In my day...

As I mentioned earlier: I've long assumed the main idea is that having clogged vascular in the brain is just another hazard to overall risk for dementia, but there was research that more directly linked neurovasculature health with the pathology of AD. The presentation by Dr. Iadecola on "Neuro...

Julie, I, too, was baffled when I thought I heard Holtzman say we are unsure whether increasing or decreasing apoe would be therapeutic. I may have to chalk that one up to misunderstanding him. As Stavia said, a lot of it was above my pay grade and many of the speakers talked at a pace that left me ...

Regarding Holtzman, AD, and sleep, check out his paper from last year...full text http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351409/ . Disturbances in the sleep–wake cycle and circadian rhythms are common symptoms of Alzheimer Disease (AD), and they have generally been considered as late consequen...

It's been a couple years since I looked, but I recall cooked plantains and bananas don't have much resistant starch. It is mainly about the raw RS2. Still useful if you eat bananas with some green on the peel.

Roasting and cooling in the fridge chopped russet potatoes (small cubes) to the point where they are browned and weigh about half their original weight was once tested as making about 50-60% of the starch resistant (RS3). The ultimate test is pre- and post- glucose testing on yourself. It is a real,...

Notes on the 3rd Annual Zilkha Symposium on Alzheimer Disease & Related Disorders: Bench to Bedside and Beyond (4/15/2016, University of Southern California, ) Yesterday, I spent the day at the Zilkha Neurgenetic Institute at USC. I wanted to share what I learned and some impressions. Overall, ...

Don't forget all those extra omega 3's...b-r-a-i-n-s...yum!

For a little bedtime reading...

Moderator note - I deleted the attached paper (10.1016/j.jalz.2016.01.008) because our copyright infringement policy prohibits it. Members in jurisdictions for which access to Sci-Hub is legal may want to search for the paper there.

FWIW, I'm also struggling with the half and half in my coffee; high SFA. I keep trying to give it up, but can't... If anyone has a decent alternative, please share. Hi Julie...OK, this is not going to work for everybody, but when I went dairy/egg free over a year ago, I also struggled with having s...