Hi there! I'm a 49 year old woman (will be 50 in May), and to be honest I'm kind of freaking out. I'm not sure if it's turning 50, or being in perimenopause, or what. But lately my anxiety and fear over alzheimer's has been through the roof. First, a brief family history. My maternal grandmother ha...

Thanks for your reply, Nancy. To add a little more info on my test, from what I could read, the Abeta 42/40 ratio is used to try to predict the formation of Amyloid plaque because (in my simple understanding) Abeta 42 goes into the plaque formation and Abeta 40 does not. If the ratio of the two in ...

Hi All, As a non-symptomatic APOE 4/4, I agreed to participate as a part of the Control Group in an ADRC study. This involves an extensive MRI session, providing a sample of CSF through LP (not fun), and annual cognitive testing. This seems worth it because it helps set a "wide perimeter fence...

Has anyone found a way to get a p-tau217 test? Getting a doctor to sign up here -- https://alzpath.bio/ -- might work, but it's not clear that AlzPath has made the test available yet. https://jamanetwork.com/journals/jamaneurology/fullarticle/2813751 Hi Brian, Thanks for sharing the full article on...

These forums are dedicated to ApoE4, but I have never observed your posts as taking on an ApoE4 viewpoint. ....you could express some greater empathy and kindness to the ApoE4 community. ... The three main themes we seem to face are lack of longevity, cardiovascular disease, and dementia. No one in...

Hi there - so we have a surprise pregnancy (but very much wanted). I am 43 but 44 in 2 weeks. I found out about my 4/4 status approx 4 years ago. I fast most days and take the recommended supplements etc. But i have been lax with my diet. My questions are , will this pregnancy ‘accelerate’ any issu...

I'm considering seeking a PET scan outside of the country. I've done some googling and found only a few locations. Some quite unusual. Is anyone aware of a published list of safe, accurate locations (likely universities?) to get a PET scan with a benchmark of accuracy internationally? My hope is th...

Does anyone know anything about CT contrast in regards to brain health? I’m supposed to have a CT w/contrast, and I’m concerned. It looks like it will be oral and IV contrast. Not happy. Thanks for any light you can shed :) Hi QueenJane! Your question is timely, since someone else asked the same th...

Hello I’m sure this has been asked before, but I’m wondering if there is a resource for genetic testing of PSEN1, PSEN2, APP without going through a Dr? The men in my mom’s family line have all started showing impairment in their late forties through sixty. I’m a very healthy 50, and I want to know...

Here's the link to register: It began today 1/16/24 thru 1/17/24- https://www.nationalacademies.org/event/41563_01-2024_research-priorities-for-preventing-and-treating-alzheimers-disease-and-related-dementias-january-workshop?utm_source=NASEM+News+and+Publications&utm_campaign=d4939c905c-EMAIL_...