Here's the link to register: It began today 1/16/24 thru 1/17/24- https://www.nationalacademies.org/event/41563_01-2024_research-priorities-for-preventing-and-treating-alzheimers-disease-and-related-dementias-january-workshop?utm_source=NASEM+News+and+Publications&utm_campaign=d4939c905c-EMAIL_...

Here's the link to register: It began today 1/16/24 thru 1/17/24- https://www.nationalacademies.org/event/41563_01-2024_research-priorities-for-preventing-and-treating-alzheimers-disease-and-related-dementias-january-workshop?utm_source=NASEM+News+and+Publications&utm_campaign=d4939c905c-EMAIL_...

I'm a 65 years old male with Alzheimer's. I was forced to retire two years ago, due to memory problems and got my official diagnosis 4,5 years ago. My grandmother and father had Alzheimer's so there seems to be a strong genetic component. At some point I was obsessed with genetics and got a full ge...

Thank you for the response. This is all so fascinating. Reading these studies can be mind-numbing. Is it your understanding that rs116558455 is common in the sense that just about everyone has it and that the variant G is the one found 99+% of the time? Or is rs116558455 a rare mutation regardless ...

NF52, this is another exciting development that you have mentioned about the AHEAD study. In the above figure the red line is where mab treatment needs to start for 95% disease slowing to occur. What you have noted is that if patients progress into early MCI while in AHEAD then they will be transfe...

I learned of this at my most recent infusion; not every person in the trial has even been notified yet since it is a December revision in the IRB consent. Thanks for sharing these updates, NF52. I imagine that this will skew the numbers in the original dataset if enough people drop out of the contr...

Louise Gray wrote: ↑Thu Jan 11, 2024 11:44 am I don’t think rs116558455 is genotyped on 23andme

So that new chip won't give me that info, but I did find the frequency on an NIH site, in case some have done whole genome sequencing. Thanks for sharing!

Thank you for the replies. I’m very surprised there is someone with a story so similar to mine! glampers I’ll private message you. The Ahead study told me I had “more than some” plaque which qualified me for the group that would receive the infusion every two weeks. I guess I didn’t ask them to be ...

I am becoming increasingly concerned that there has yet to be any acknowledgment of the report from CTAD about the 95% claim. There are so many millions of people that have been progressing into further cognitive decline and moving closer to the point of no return over the last few months; simply i...

"Two mutations (rs116558455 and rs140926439) in the FN1 gene (Fibronectin-1) were found in healthy elderly ε4 homozygous carriers in EFIGA/WHICAP and NIA AD-FBS cohorts with MAF=1.85% and 3.33%, respectively..." Do you interpret the above sentence from the study to mean that the healthy e...