Did you also make some changes to the keto diet? As per the other thread, I've been tinkering with my diet to add more carbs, heading towards somewhere around 150 grams net carbs per day. In addition to low numbers of certain microbiome strains (that are carb lovers), I also have trouble keeping on...

This issue is probably more nuanced than choline = TMA = heart disease. I posted this article in another thread, but thought it would be useful to this discussion. Bottom line with any associative study is we don't understand what folks are eating besides meat or eggs (or anything else for that matt...

Hormone replacement therapy is associated with improved cognition and larger brain volumes in at-risk APOE4 women: results from the European Prevention of Alzheimer’s Disease (EPAD) cohort The study shows that HRT use is associated with better memory, cognition and larger brain volumes in later lif...

Erythritol Functional Roles in Oral-Systemic Health Oral health studies revealed that erythritol can reduce dental plaque weight, reduce dental plaque acids, reduce counts of mutans streptococci in saliva and dental plaque, and reduce the risk for dental caries better than sorbitol and xylitol, res...

When you say "minor allele" are you saying that "G" is the non-protective version that is usually associated with ApoE4? The paper I cited earlier in this thread said "G" increases the risk. Sorry, we all hope to win the genetic lottery to modify E4 effects, but someti...

adriana268 wrote:do you mean you saw a status if tomm40 on your old 23 and me report ?

It's not in any reports. You have to click the "Browse Raw Data" in the dropdown menu under your name. Then put rs2075650 in the search box and read the results. "G" is the minor allele.

Beyond viral infection as a trigger to Alzheimers, we now may also have "jumping genes." Alzheimer's disease and progressive supranuclear palsy are marked by toxic deposits of a protein called tau. Their research found that tau-induced "jumping genes" -- which can relocate or cop...

Do you know the advantages of taking Citicoline versus Phosphatidylcholine? I think it depends on what your goals are. Choline gets metabolized differently depending on your body's needs. For example, I'm post-menopausal and have PEMT variants that suggest that Phosphatidylcholine (skipping the PEM...

Chrisweides wrote:You could maybe pm me. I feel I need to go to the doctor armed with knowledge.

I will message you with some info.

Do you know if these additional snips are reported in 23 and Me? I did not listen to the podcast, but here is a recent research article about those genes. From: Definitive roles of TOMM40-APOE-APOC1 variants in the Alzheimer's risk (2022) We report the remarkably high excesses of the AD risk for ca...