Well, there is (one) study that shows alcohol (even moderate) is detrimental for E4s. I suspect that in the past alcohol helped longevity because it killed microbes. For example, in the london cholera outbreaks (before they learned not to eject sewage upstream of water intake in river), those that d...

That seemed like more of an opinion. It looked (to us close to a decade ago) that amyloid plaques were more of a marker than a cause. Yet many trials continued to find ways to remove it. Each experiment that worked at removing plaques, also made the cognition worse. Odd that they kept running new tr...

interesting about the weight on the heel. I'll have to try that. My max has been 11 steps and 6 or 8 is more like the usual. My trees are about 45' apart and I understand that a tighter line is easier, with a shorter distance. I also have a 2" wide line with a ratchet like from ratchet straps ...

What about inversion? A friend recently mentioned it's been shown to help thyroid issues, presumably because of blood flow - so it seems it would help the brain. I'm already doing a couple of poses for stretching (like downward dog), so why not?

S

I enjoy myself more when I'm healthy. So far, generally everything that mitigates AD risk also mitigates other diseases.

So far, the countermeasures are enjoyable also.


S

I'm in, if possible

I've read there are different separate benefits with HIIT, moderate exercise and endurance excercise for BDNF and mitochondria. My guess is try to fit in all 3 to be optimal, but I have no idea of the perfect way to mix it up ...

FYI, I think the recommended dosingfor mk4 is different than MK7 (mK7 considerably less) , which sometimes leads to confusion.

curcumin also reduces the expression of PAI-1

Oh cool! Will we have access to our own data?