I'm in!

Results held up after controlling for APOE genotype. Results support pupillary response—and by inference, LC dysfunction—as a genetically-mediated biomarker of early MCI/AD risk. In combination with other biomarkers, task-evoked pupillary responses may provide additional information for early screen...

They found 2 SNP's that seemed to have "strong evidence" for resilience (CASP7 rs10553596 and SERPINA3 rs4934-A/A). Thanks for posting broiler, I checked on my Promethease results (from my 23&me data), and it didn't have the CASP7 one and for the SERPINA3 it states: "rs4934 incre...

A note on that last point. I remember a Peter Attia podcast episode with Rhonda Patrick where they talk about saturated fat intake on a keto diet. In their own clinical experience, roughly 15% or so of their patients responded in a way that greatly increased their LDL-p (Low-Density-Cholesterol Lip...

Does anyone wear a fitbit? if so, how much DEEP sleep do you get each night? J. I recently bought an Oura ring and have been comparing it to my Fitbit. I haven't done a full excel spreadsheet comparison, but over the last five nights they show my deep sleep as: Saturday 31 min (FB) 80 min (O), rati...

Scientists debate, and one company targets gingivitis bacterium to slow Alzheimer's progression https://www.medpagetoday.com/meetingcoverage/aaic/81065?xid=nl_mpt_DHE_2019-07-18&eun=g1321960d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%202019-07-18&utm_t...

Predicting Alzheimer's Blood markers close in on helping determine who will develop Alzheimer's disease “LOS ANGELES -- Blood samples taken over several years from cognitively normal people predicted who would develop Alzheimer's disease with high discrimination accuracy and specificity about 4 year...

I'm in. Not having grown up in the Bay Area, these meetings give me an opportunity to visit new neighborhoods. SR sounds good to me. Chris Yes, it was nice to see folks again, and catch up on what each is doing. How does Sunday, October 13, 2019 at 10 am sound for the next one? I'm thinking that San...

I would definitely err on the side of caution with meat. There are too many studies showing its deleterious effects on AD. Hi Plumster, thanks for that link. Here's one quote of interest: "Foods protective against AD include fruits, vegetables, grains, low-fat dairy products, legumes, and fish...

I found the first hour rather repetitive and I thought Peter Attia didn't challenge Dr. Fung very much since his work was based on clinical results. What I did like was that Dr. Fung said that his observations were limited to those very sick and said that fasting is low risk with potential high gain...