The 68 year mean onset age seems a little low. I have heard 73 year mean onset age used more often.We 4/4's get it 5 years earlier on average than 3/4's and 10 years earlier than 3/3's. This exact symmetry of " years difference in onset" has always fascinated me as it is the beauty of larg...

Thank you for participating in the research!

I agree there really is no risk in pounding down a bottle of Fiji Water each day other than the $1 more it costs. I drank one today and have been drinking them for awhile now. I am going to place a small bet on silica but I am also going to cover my bet on Silica by placing larger bets on other seem...

I think it's pretty clear that Amyloid is an anti-microbial. I think it's pretty clear that some pathogens (UTI, Herpes Simplex Viruses ) exacerbate, contribute to or are a majority cause of MCI or Alzheimer's. Antedotaly my mother who now has full blown Alzheimer's had MCI that became Alzheimer's a...

Peter Attia's Podcasts are some of the best non-dummied-down medical information on the web. I really like hearing him talk shop with his various guests. His notes on the podcasts are great as I am typically a little short on time to watch every podcast fully. My opinion is don't get too bogged down...

The protein cycling looks interesting. Very thorough discussion with what "appears" to be some empirical data. The author does say err on the side of not getting too low on protein when reducing intake while cycling. I have wondered about the autophagy question for some time. Like Brian I ...

Define specifically what autophagy is? We have some image of our body cleaning out unusable matter, dead cells, cancer cells etc. because it can clean house now that it doesn't have to deal with all that food coming in. It seems like the process is more complex than this? From Dr.Google: How long do...

Thanks Laurie -- Below is the link to the worldlifeexpectancy.com listings of Alzheimer's dementia by country. However, I remain skeptical about the reliability. The table implies for example that Alzheimer's is 164 times more prevalent in Finland than in Singapore. One would think that would be wi...

I am not an expert on any of this and what I am telling you is a regurgitation of information that is an educated guess. 1. The current dental X-Rays have a fraction of the radiation that they had years ago. 2. Radiation is bad as it relates to risk of cancer but it is dose dependent meaning a highe...

Having too low a level of insulin or even IGF will increase your risk of Dimentia ! Dr Bredesen discusses this in his book as Type 2 atrophic Dementia. Dr. Gundry points out that the people at greatest risk in the Framingham Study were low BMI Women with high adiponectin levels. Obesity in Mid life ...