Search found 1938 matches

by NF52
Sun Apr 07, 2024 10:51 am
Forum: Prevention and Treatment
Topic: Periodontitis / Gingivitis / Gum Disease in E4/E4
Replies: 32
Views: 36822

Re: Periodontitis / Gingivitis / Gum Disease in E4/E4

Hi all. Been reading through the forum and thought I would chime in with my personal experience… Shied away from the dentist for just over twenty years but reluctantly set up an appointment after my wife mentioned I had halitosis. I also had high sensitivity to hot and cold liquids. Because I hated...
by NF52
Thu Apr 04, 2024 10:19 am
Forum: Announcements and Events
Topic: A heart-warming movie about FTD & Early-Onset Dementia
Replies: 0
Views: 14573

A heart-warming movie about FTD & Early-Onset Dementia

On Thursday, April 25 at 6:00 PM Eastern time, Mass General and the Massachusetts Alzheimer's Disease Research Center will have a short film that might be worth watching: Pedacito de Carne follows a young millennial Hispanic woman caring for her mother living with young-onset dementia, as both wome...
by NF52
Wed Apr 03, 2024 9:25 am
Forum: Science and Research
Topic: Huge list of therapies / drugs in the pipeline
Replies: 4
Views: 14730

Re: Huge list of therapies / drugs in the pipeline

Therapies in the pipeline. There are so many but few specifically targeted at apoe4/4 Short take: BCG, pertussis vaccines look interesting, valacyclovir. Can be done with no concerns about side effects. Also LX1001 apoe2 gene therapy and Trappsol Cyclo (Cyclodextrin) are of interest to me. Thanks f...
by NF52
Wed Mar 27, 2024 9:37 am
Forum: Our Stories
Topic: 24 and 4/4
Replies: 7
Views: 8908

Re: 24 and 4/4

Hi all, I’m really really sad to be joining this forum. I found out today that I’m 4/4 for APOE4 and have no idea where to start. I’m 24, just graduated college, I have no family history of dementia or AZ (I did lose my grandfather in his late 60s to a heart attack though, so there’s some cardiac b...
by NF52
Tue Mar 26, 2024 7:20 am
Forum: Our Stories
Topic: NEW LIKELY CAREGIVER HERE.
Replies: 12
Views: 10709

Re: NEW LIKELY CAREGIVER HERE.

Hi Nancy! I am following your advice and looking at joining the website. I know I am going to sound out of bounds, but the $75 monthly costs to locate the trained person in my area might be tough. I get that this is life or death. That is what also makes it somewhat astonishing that there is a fee ...
by NF52
Tue Mar 26, 2024 5:11 am
Forum: Prevention and Treatment
Topic: Methylene Blue: OLE results from Lucidity Trial at Lisbon AD/PD
Replies: 3
Views: 6547

Re: Methylene Blue: OLE results from Lucidity Trial at Lisbon AD/PD

Thanks for sharing this! Over the years I've wondered why clinical trial results were so unclear most of the time, compared to the earlier studies in animals or cell cultures, where the results are usually clear. Sample sizes, I suppose, and the fact that animals cooperate better, and can't drop ou...
by NF52
Mon Mar 25, 2024 9:05 am
Forum: Our Stories
Topic: NEW LIKELY CAREGIVER HERE.
Replies: 12
Views: 10709

Re: NEW LIKELY CAREGIVER HERE.

That is being considered as well. Thanks Not sure how to look. Know of anyone near 76001 which is Dallas/Fort Worth Texas? Thanks for the comment. Hi again, If you want to consider someone trained in the Bredesen protocol in the Dallas/Fort Worth area, you have a few options. You can use the search...
by NF52
Mon Mar 25, 2024 8:33 am
Forum: Prevention and Treatment
Topic: Methylene Blue: OLE results from Lucidity Trial at Lisbon AD/PD
Replies: 3
Views: 6547

Methylene Blue: OLE results from Lucidity Trial at Lisbon AD/PD

The newest issue of Alzforum has an article on the presentation of results from the open-label extension of the Lucidity trial of HMTM, a derivative of methylene blue, at the March 2024 AD/PD conference in Lisbon. Here's the article and an excerpt: TauRx Parses Subgroups to Make the Case for Methyle...
by NF52
Sun Mar 24, 2024 5:58 pm
Forum: Our Stories
Topic: NEW LIKELY CAREGIVER HERE.
Replies: 12
Views: 10709

Re: NEW LIKELY CAREGIVER HERE.

My wife was recently diagnosed with EOAL. Age 54, and height/weight lean and for the most part healthful. We were doing basic testing with a Neurologist over a few years and he leaned towards depression. Now at UTSW in which test results have confirmed. The lumbar tests resulted in high PTAU and a ...
by NF52
Fri Mar 22, 2024 11:18 am
Forum: Getting Started
Topic: APOE4/4 makes it to age 86!
Replies: 9
Views: 9633

Re: APOE4/4 makes it to age 86!

Bruxism is characteristic of very late stage ALZ which is consistent with her being on Aricept for about 8 years now. She was deemed "un-testable" for cognitive testing when we brought her in a few years ago. I'm curious if she's had a recent MRI of her brain...Given that your mom is a 4/...