Hi aphorist. That is a bit dense, isn't it? I've been trying to keep up, typing out notes after working remotely. I find everything is a bit harder. I have a few more to enter - I've fallen a bit behind. Will try to organize them better.

Seminar #3. Rik can der Kant. Cholesterol and apoe4. Prof. van der Kant specializes in cholesterol metabolism and is applying this apoe4 models. He began by discussing how human cells can be converted in stem cells, then into almost any other type of cells - which is useful for making apoe4 populati...

A collection new articles about APOE4 and fuels, the western diet, potential drugs, the role in disease, the role in heahlty brain: ApoE in Alzheimer Disease and Neurodegeneration Edited by Allan Butterfield, Lance Johnson Last update 26 March 2020 Neurobiology of Disease will be publishing a speci...

Saw this and agree. It seems important!

Hi everyone. Thanks very much for your kind comments.

Seminar 2. Gareth Howell. The Jackson Lab. MODEL-AD: Towards the next generation of mouse models for Alzheimer's disease. The general idea was that progress in AD has been slowed by poor mouse models. They participate in the MODEL-AD group, hundreds of researchers, working to create and test better ...

Some notes from the first two seminars: Seminar #1. March 26. Lance Johnson (U. Kentucky). Tipping the energy balance: APOE, AD and cerebral metabolism. Dr. Johnson started by explaining the theory that apoe4 carriers use "fuels" differently. Specifically, that apoe4 astrocytes and microgl...

Oh no. Sorry, I misread that.

I took notes and plan to post summaries here, if that helps.

I haven't tried that yet but I think the directions are buried in those tweets. There has been only one recorded so far. I'll look into it and report back....

For those interested in the nuts and bolts details of AD research I wanted to let you know of a Alzheimer's Afternoons Seminar Series that is occurring online during the COVID-19 shut down. It is focused on apoe. It is run by a group of researchers as a lab seminar series, organized via Twitter by A...