What a difference you are making for so many people! Your passion, intelligence and kindness is evident in everything you do. Happy Birthday.

The article link is behind a Wall Street Journal subscription wall. Can anyone find another link or copy? Thanks.

Walkinlab.com has a 20% off sale through today Memorial Day. They have full NMR tests. http://www.walkinlab.com

GeorgeN wrote:

Matisse wrote:May I ask who he is and where he is (w/o downloading)? Thanks.

Phone: 303-443-7226
Fax: 303-443-7168
William L. Blanchet, MD
2880 Folsom, Suite 100
Boulder, Colorado 80304

The link to his website is in my post above .

Thank you George.

May I ask who he is and where he is (w/o downloading)? Thanks.

From a new study: "Patients homozygous for the rs4680 low-activity met allele (met/met), known to have high levels of dopamine, had the greatest placebo response. The high-activity val allele homozygous (val/val) patients had the lowest placebo response." Met/met is AA. Val/val is GG. Here...

RS4420638 is another snp that is in strong but not perfect LD with apoe. Usually apoe3/3 is AA but some people with apoe3/4 are also AA. It doesn't tend to go the other way however -- that is someone who is 3/3 will not be AG.

I actually have a PSEN1 mutation of possible concern, no PSEN2s. No history of early onset dementia in my family and I'm 64. Just wondering whether Doc got any more info on the PSENs.

Doc,

Did you ever pursue the study at the U of Washington. I also have a PSEN mutation -- not sure how serious it is -- but am still concerned so I'm wondering what your experience has been with them. Thanks.

Matisse

JanPeter,

Have you looked at your snps related to methylation especially the serotonin/dopamine ones?

http://geneticgenie.org/methylation-analysis-example/

Matisse