Rauch, J., Luna, G., Guzman, E., Audouard, M., Challis, C., & Sibih, Y. et al. (2020). LRP1 is a master regulator of tau uptake and spread. Nature. doi:10.1038/s41586-020-2156-5 Abstract The spread of protein aggregates during disease progression is a common theme underlying many neurodegenerati...

Fiver wrote:I took notes and plan to post summaries here, if that helps.

If you can post yesterday's summar, I'd be interested. I just saw this link you provided and yesterday's topic looks interesting. Today, not so much.

Selenium is an important nutrient. It's important to not be deficient in any vitamin or mineral going into a virus. But what Dr. Crouse appears to do is take his background and underlying concerns in ROS/metal ions and then shoehorn it into a solution for a viral lung infection. His logic reads to m...

Overall, full-scale IQ scores were lower by 1.91 points for each APOE4 allele an individual carried. A person can have up to two APOE4 alleles, and the gene's effect on IQ performance multiplies with each allele present. Boys scored .33 points lower on IQ tests, and girls scored almost 3 points low...

First clinical trial for Coronavirus - 24 G IV infusion of Vitamin C https://clinicaltrials.gov/ct2/show/NCT04264533 It's a very high amount, probably to prove efficacy. Normal IV's are like 10-15 grams. But, long story short if you have some vitamin C daily... even like 200 mg, it will likely help...

First clinical trial for Coronavirus - 24 G IV infusion of Vitamin C https://clinicaltrials.gov/ct2/show/NCT04264533 It's a very high amount, probably to prove efficacy. Normal IV's are like 10-15 grams. But, long story short if you have some vitamin C daily... even like 200 mg, it will likely help ...

Decent overview. Horrible intro music. He needs to be checked for dementia for inserting that for 3 minutes in the beginning.

In my estimation, this paper is huge. It mechanistically shows how Abeta initiates the cascade to phospho-tau. Shows how idazoxan and lithium inhibit phospho-tau and rescue alzheimer's. This paper is just enormously important. https://www.alzforum.org/news/research-news/shot-adrenaline-amyloid-v-sp...

I can't figure out the conversion on those figures. The data I have is in nmol/L.

Thanks, Aphorist, my B12 plasma levels are never that low (always 1500 or above), even when I stop supplementing for a few days before a test. (Perhaps I need to stop supplementing for a whole week before a blood draw?) Recently, I was asked to increase my daily dose due to my MMA levels indicating...