Looking at many genes may be more helpful to understand ones physiology. Andru, You might want to look at genome-wide associations. https://forums.apoe4.info/viewtopic.php?f=16&t=4278&p=50072&hilit=genome+wide+association#p50072 Two homozygous APOE4 carriers might show different outcome...

Andru, The high-intensity sprints are probably giving you a lot of bang for your buck. Doing bodyweight exercises helps because it removes the hurdle of getting to a gym. High intensity interval training, adapted to limitations, is near the top of my list of recommended healthy habits. Doing activit...

Andru, Good to have you here. You seem to have chosen your parents wisely, for an E4 carrier. 6-8% body fat with a healthy BMI is better than some professional athletes. Which foods give you saturated fats? And what are your regular physical activities? 30 is about the age when brain development sta...

I'd be interested to learn more, if anyone has thoughts about this or knows of interesting studies. Especially if there seemed to be a point in the cycle where people could exert some control.....relaxing, meditating, getting a dog, using SSRIs, etc. Personality might be less permanent than previou...

It's a crude surgical procedure for delivery, and included only a few subjects with Parkinson's disease. They switched on synthesis of a specific protein in an area of the brain. As safety and methods of delivery improve, those with a predisposition to other age-related diseases might hope for effec...

Tincup, You'd better survive to a ripe old age in good working order, with everything you're doing. :) Otherwise everyone might start overeating, sitting for hours at a stretch, wrapping up against the cold winters, drinking lots of spirits, sleeping at odd hours, stressing out etc. I have a hunch t...

Sauna bathing is inversely associated with dementia and Alzheimer's disease in middle-aged Finnish men. https://www.ncbi.nlm.nih.gov/pubmed/27932366 I have wanted to get a NI sauna for a while now. Anyone have a sauna they love? That is quite impressive, given that they controlled for many potentia...

Before I looked at all of this so "scientifically" I was well into my habits of meditation, playing raquetball, traveling, enjoying family and taking my "yellow stuff" daily. Now that everything is going so "factual" I find myself worrying more. That sounds like a life...

The insulin level will vary with glycemic index of the ingested food, and with time of day. Also with beta-cell function. Most information for reference ranges is probably available for overnight fasting followed by 75 g glucose ingested in the morning. Then blood drawn 2 hours later. An excessively...

This makes life really good for searchers.