Search found 5565 matches

by circular
Wed Mar 04, 2015 4:25 pm
Forum: Science and Research
Topic: Analysis of European mitochondrial haplogroups with Alzheimer disease risk
Replies: 19
Views: 7485

Re: Analysis of European mitochondrial haplogroups with Alzheimer disease risk

Rep, I think you answered your own question: "How can we explain the previous findings? The strict maternal inheritance of mammalian mtDNA and the associated lack of intermolecular recombination renders mtDNA genetic association studies particularly vulnerable to a population stratification eff...
by circular
Wed Mar 04, 2015 4:04 pm
Forum: Prevention and Treatment
Topic: Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets - 2013
Replies: 4
Views: 2082

Re: Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets - 2013

AB4M, I have those dang histamine issues too. I finally cut canned fish out of my diet - I was eating Wild Planet sardines and Crown Prince salmon with bones and skin. Those seemed to be worse than ... wait for it ... flying in flash frozen salmon! I eat it fewer times a week due to the cost, but it...
by circular
Wed Mar 04, 2015 10:57 am
Forum: Science and Research
Topic: Alzheimer's Disease Is Type 3 Diabetes–Evidence Reviewed
Replies: 2
Views: 1785

Re: Alzheimer's Disease Is Type 3 Diabetes–Evidence Reviewed

Nice. This is why I figured they were calling it "Type III D". It's also why I haven't felt confident that having good post-prandial BG measurements is enough to conclude there's no glucose metabolism impairment in my brain. But like you say, if all the other cofactors are healthy we have ...
by circular
Tue Mar 03, 2015 10:40 pm
Forum: Prevention and Treatment
Topic: A new understanding of Alzheimer’s
Replies: 15
Views: 5644

Re: A new understanding of Alzheimer’s

The part that was new to me wasn't the mitochondrial involvement but the notion that impaired neurons up regulate their energy intake and thus rob healthy neurons of the energy they need, so both camps thereby head downhill. The Science Friday piece is a good synopsis to send menopausal women. Scare...
by circular
Tue Mar 03, 2015 10:23 am
Forum: Science and Research
Topic: Excellent set of slides
Replies: 7
Views: 3205

Re: Excellent set of slides

Hmmm, looks good. Wish I could have listened to the talk and I might take in more :-) One thing that stands out, if I skimmed it right, is that suppressing inflammation may undesirably suppress beneficial neuromodulation being performed by the immune system, and modifying immune function may have di...
by circular
Tue Mar 03, 2015 10:12 am
Forum: Science and Research
Topic: Excellent set of slides
Replies: 7
Views: 3205

Re: Excellent set of slides

Lilly how did you find out your Klotho KL-VS variant? I don't see it in Promethease?
by circular
Mon Mar 02, 2015 3:13 pm
Forum: Prevention and Treatment
Topic: Quercetin
Replies: 19
Views: 8156

Re: Quercetin

Why are the benefits of matcha less variable?
by circular
Mon Mar 02, 2015 11:15 am
Forum: Prevention and Treatment
Topic: "Leaky Blood-Brain Barrier a Harbinger of Alzheimer's?"
Replies: 4
Views: 2026

Re: "Leaky Blood-Brain Barrier a Harbinger of Alzheimer's?"

I think lectins in foods are associated with leaky intestinal barrier, so maybe also BBB once they're in the bloodstream? This is one of my big problems with low animal protein, higher plant protein diets, at least for me. The plant proteins seem invariably to contain lectins: beans and legumes and ...
by circular
Mon Mar 02, 2015 10:35 am
Forum: Prevention and Treatment
Topic: "Leaky Blood-Brain Barrier a Harbinger of Alzheimer's?"
Replies: 4
Views: 2026

"Leaky Blood-Brain Barrier a Harbinger of Alzheimer's?"

Webinar and slides now online.

I noted that in Dr. Bredesen's recent talks he recommended Cyrex Assays. They have one for the BBB. Anyone know what it costs?

http://www.alzforum.org/webinars/leaky- ... alzheimers