Search found 629 matches

by Fiver
Tue Feb 11, 2020 6:50 am
Forum: Science and Research
Topic: 2019 review on APOE4 and AD
Replies: 1
Views: 1179

Re: 2019 review on APOE4 and AD

I read this. Thanks for sharing! It's a good overview of the current apoe4 research. It might be worth linking somewhere for new folks. I wish they were further along on these approaches to addressing apoe4 directly.
by Fiver
Mon Feb 03, 2020 1:02 pm
Forum: Science and Research
Topic: Plant flavonols significantly reduce Alzheimer’s risk
Replies: 8
Views: 3136

Re: Plant flavonols significantly reduce Alzheimer’s risk

I love plant polyphenols and I'm not surprised that they reduce risk. They found reduced risk associated with kaempferol, myricetin, and isorhamnetin. They state they found not risk reduction associated with quercetin but their data kind of suggests that a larger study might detect that as well. I'm...
by Fiver
Sun Feb 02, 2020 12:31 pm
Forum: Science and Research
Topic: NIH grants Gladstone Institute $4.8M to study ApoE4
Replies: 2
Views: 1372

Re: NIH grants Gladstone Institute $4.8M to study ApoE4

Years back I had high hopes for their apoe4 "structure correcters" That research hasn't seemed to move along as quickly as hoped. But I'm glad they're still at it!
by Fiver
Sun Feb 02, 2020 12:29 pm
Forum: Our Stories
Topic: Just discovered I'm 4/4, rocked.
Replies: 23
Views: 8887

Re: Just discovered I'm 4/4, rocked.

A similar experience here, though I am a bit older at 48. You've found the right place. Welcome to the group!
by Fiver
Thu Jan 16, 2020 6:46 am
Forum: Prevention and Treatment
Topic: Air pollution and apoe4 - bad to worse
Replies: 0
Views: 569

Air pollution and apoe4 - bad to worse

92% of people live in places where particulate matter pollution exceeds the World Health Organization’s guideline for healthy air. The gene variant, which ~25% of people possess, ApoE4 increases the risk that exposure to air pollution leads to #Alzheimers. https://nyti.ms/2TjBgpL Why Is Air Pollutio...
by Fiver
Wed Jan 15, 2020 12:08 pm
Forum: Prevention and Treatment
Topic: Zero carb diet will help prevent Alzheimer’s
Replies: 126
Views: 58436

Re: Zero carb diet will help prevent Alzheimer’s

Good point! Inflammation is important, and we can measure that. I actually did that, and saw inflammation go down at the time I made some changes. I hadn't thought of that in a while.
by Fiver
Mon Jan 13, 2020 7:47 am
Forum: Getting Started
Topic: Just got results, I carry 2 E4 genes, I have questions!
Replies: 5
Views: 3206

Re: Just got results, I carry 2 E4 genes, I have questions!

Hi. I'm not an expert or medical doctor. I just like reading about this. For what it is worth I'm not aware of any studies showing strong, direct links between apoe4 and these particular symptoms. But I can think of lots of indirect ways in which they could be related. So a search of the literature ...
by Fiver
Mon Jan 13, 2020 7:39 am
Forum: Prevention and Treatment
Topic: Zero carb diet will help prevent Alzheimer’s
Replies: 126
Views: 58436

Re: Zero carb diet will help prevent Alzheimer’s

Hi dfmcapecod, I remember that thread from the summer! I guess we're all waiting on that diagnostic test to come along. :? There was another flurry of news about blood and spinal fluid tests for AB and tau recently. If those come to fruition I suppose we could all evaluate how our lifestyle interven...
by Fiver
Fri Jan 10, 2020 10:20 am
Forum: Prevention and Treatment
Topic: statins and antibiotics together
Replies: 4
Views: 2066

Re: statins and antibiotics together

NF52 is spot on, once again, in my opinion. :D (oh, and Slacker too!) The debate about statins is a long one. The best course of action almost certainly depends on our own situations. I've been on low dose statins, of various sorts, for 3-4 years now. The research convinced me that overall the benef...
by Fiver
Fri Jan 10, 2020 8:05 am
Forum: Our Stories
Topic: "Freaking out" update
Replies: 3
Views: 1511

Re: "Freaking out" update

Congrats on all the great lifestyle changes! It's good motivation for me.