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by Fiver
Fri Sep 13, 2019 12:10 pm
Forum: Prevention and Treatment
Topic: Cleaning of Lymphatic brain vessel - Nasya therapy
Replies: 21
Views: 4464

Re: Cleaning of Lymphatic brain vessel - Nasya therapy

Thanks. very interesting! I think this is what I am learning: Looks like several things might be going on. Cell shrink and swell, which would involve the aquaporins to let water in and out of cells. Then there is some sort of space, tubes or openings. And these become more open or more constricted d...
by Fiver
Thu Sep 12, 2019 8:40 am
Forum: Prevention and Treatment
Topic: UsAgainstAlzheimers report: non-pharmacological interventions
Replies: 2
Views: 673

Re: UsAgainstAlzheimers report: non-pharmacological interventions

Thanks Julie. That's also a interesting site. (when I saw that they list statins as having solid evidence supporting moderate benefit I imagined the debate that might cause, though it does seem - at least to me - to be an accurate rating). It is interesting what happens in society as evidence for no...
by Fiver
Wed Sep 11, 2019 11:17 am
Forum: Prevention and Treatment
Topic: UsAgainstAlzheimers report: non-pharmacological interventions
Replies: 2
Views: 673

UsAgainstAlzheimers report: non-pharmacological interventions

Anyone seen this yet? I read the report, which reads like a journal review article but as far as I can tell is not published in a peer-reviewed journal. But it seems useful and legit, ranking various non-pharmacological interventions by the strength of supporting evidence. Link Below. Washington, D...
by Fiver
Wed Sep 11, 2019 10:01 am
Forum: Our Stories
Topic: I guess I'll be taking a statin
Replies: 52
Views: 13432

Re: I guess I'll be taking a statin

Don't worry too much about whether or not anyone "is confused" about blood cholesterol and lipids. I know highly trained cardiologists and lipodemiologists who admit that *no one* understands this. We're all trying to make the best possible choices with incomplete information. It seems lik...
by Fiver
Wed Sep 11, 2019 7:08 am
Forum: Prevention and Treatment
Topic: "Lifetime risk for APOE4/4 carriers is 30% because they'll likely die from heart disease" - is this research outdated?
Replies: 5
Views: 1519

Re: "Lifetime risk for APOE4/4 carriers is 30% because they'll likely die from heart disease" - is this research outdate

Sometimes I can absorb data like this objectively and scientifically. Sometimes my first response is a wave a dread and worry. Depends on the day. My calcium score was zero - which was reassuring. But I have had close relatives have early life heart attacks too. I try to use statements like this to ...
by Fiver
Mon Sep 09, 2019 10:20 am
Forum: Our Stories
Topic: Little freaked out, but I suppose it's normal.
Replies: 5
Views: 1308

Re: Little freaked out, but I suppose it's normal.

Totally normal. Sounds like you are using the information to improve your health overall. That's the good part of this wild ride.
by Fiver
Fri Sep 06, 2019 6:27 am
Forum: Prevention and Treatment
Topic: Epigenetics - can we really turn APOE4 off?
Replies: 30
Views: 7484

Re: Epigenetics - can we really turn APOE4 off?

I guess this new news article relates to our discussion of epigenetics.... First hint that body’s ‘biological age’ can be reversed In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’, which tracks a person’s biological age. https://www.nature.com/articles/d41586-019-02638-w?ut...
by Fiver
Wed Sep 04, 2019 10:15 am
Forum: Prevention and Treatment
Topic: Cleaning of Lymphatic brain vessel - Nasya therapy
Replies: 21
Views: 4464

Re: Cleaning of Lymphatic brain vessel - Nasya therapy

I've often wondered how this would work. The connections must be small and there must be some positive pressure from the brain, pushing fluid outward - else pathogens could get in. Seems like the flow of substances out of the brain would depend upon the size of the "tubes" and the pressure...
by Fiver
Mon Sep 02, 2019 10:00 am
Forum: Prevention and Treatment
Topic: Epigenetics - can we really turn APOE4 off?
Replies: 30
Views: 7484

Re: Epigenetics - can we really turn APOE4 off?

Hi Michae_M. I recall being encouraged by the structure corrector studies a few years back but so far it does not seem to have made much progress. It seems the biotech companies of finding more difficult than anticipated in people, compared to cell culture and mice. this approach seems to have the o...
by Fiver
Fri Aug 30, 2019 1:11 pm
Forum: Prevention and Treatment
Topic: Epigenetics - can we really turn APOE4 off?
Replies: 30
Views: 7484

Re: Epigenetics - can we really turn APOE4 off?

Hi Julie, I was trying to get through this one yesterday and got side-tracked. I'd believe epi-genetics is a part of it. Though the work on the genes themselves - apoe4 and others - is also pretty convincing. There are three basic epi-genetic systems, which place or remove "epigenetic" mar...

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